Evidence map›Paper›PMID 35107994›Full record

ArticleACS nano2022

Dextran-Mimetic Quantum Dots for Multimodal Macrophage Imaging

Hongping Deng, Christian J Konopka, Suma Prabhu, Suresh Sarkar, Natalia Gonzalez Medina, Muhammad Fayyaz, Opeyemi H Arogundade, Hashni Epa Vidana Gamage, Sayyed Hamed Shahoei, Duncan Nall and 11 more

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Targeted drug delivery systems for atherosclerosis.Journal of nanobiotechnology · 2025
    Review
  8. Article
  9. Nano Delivery System for Atherosclerosis.Journal of functional biomaterials · 2024
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. HSA-ZW800-PEG for Enhanced Optophysical Stability and Tumor Targeting.International journal of molecular sciences · 2023
    Article
  15. Nanomedicine for Diagnosis and Treatment of Atherosclerosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  16. Advances in macrophage-targeting nanoparticles for the diagnosis and treatment of inflammatory bowel disease.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2023
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 2 countries.

Hongping DengDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0003-1154-8656
Christian J KonopkaDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0001-6789-3702
Suma PrabhuDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Suresh SarkarDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Natalia Gonzalez MedinaDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Muhammad FayyazDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Opeyemi H ArogundadeDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Hashni Epa Vidana GamageDepartment of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Sayyed Hamed ShahoeiDepartment of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Duncan NallDepartment of Physics and Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Yeoan YounCenter for Biophysics and Quantitative Biology and Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Iwona T DobruckaDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Christopher O AuduDepartment of Surgery, University of Michigan, Ann Arbor, Michigan 48109, United States.
Amrita JoshiDepartment of Surgery, University of Michigan, Ann Arbor, Michigan 48109, United States.
William J MelvinDepartment of Surgery, University of Michigan, Ann Arbor, Michigan 48109, United States.
Katherine A GallagherDepartment of Surgery, University of Michigan, Ann Arbor, Michigan 48109, United States.
Paul R SelvinDepartment of Physics and Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0002-7632-8163
Erik R NelsonDepartment of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Lawrence W DobruckiDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0002-6807-217X
Kelly S SwansonDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0001-5518-3076
Andrew M SmithDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0002-0238-4816
University of Illinois Urbana-Champaign · USUniversity of Michigan · US

Funding

Targeting jmjd3 mitigates heterotopic ossificationR01AR079863 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Katherine Ann Gallagher, Benjamin Levi · 2021 to 2026
$3.0M
Notch signaling in diabetic woundsR01DK127531 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GALLAGHER, KATHERINE ANN · 2021 to 2024
$2.5M
Targeted Drug Delivery to Adipose Tissue Macrophages in ObesityR01DK112251 · NIDDK · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SMITH, ANDREW MICHAEL, SWANSON, KELLY S · 2016 to 2020
$2.1M
Epigenetic Regulation of Prostaglandin E2 (PGE2) Synthesis Alters Macrophage Function to Promote Inflammation and Impair Diabetic Wound HealingR01DK124290 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GALLAGHER, KATHERINE ANN, MOORE, BETHANY B. · 2020 to 2023
$1.8M
Impact of cholesterol and its metabolites on breast cancer progressionR01CA234025 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI NELSON, ERIK RUSSELL · 2019 to 2023
$1.7M
JMJD3 Regulates Abdominal Aortic Aneurysm ExpansionR01HL156274 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GALLAGHER, KATHERINE ANN · 2021 to 2022
$1.1M
Toll-like Receptor 4 and Transforming Growth Factor Beta Receptor Stimulation in Macrophages Regulate Prostaglandin-mediated Inflammation and Direct Wound HealingF32HL152508 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MELVIN, WILLIAM JAMES · 2021 to 2021
$67k
NCI NIH HHS R01 CA234025NHLBI NIH HHS F32 HL152508NHLBI NIH HHS R01 HL156274NIAMS NIH HHS R01 AR079863NIDDK NIH HHS R01 DK112251NIDDK NIH HHS R01 DK124290NIDDK NIH HHS R01 DK127531
6 · The paper itself

Abstract

Macrophages are white blood cells with diverse functions contributing to a healthy immune response as well as the pathogenesis of cancer, osteoarthritis, atherosclerosis, and obesity. Due to their pleiotropic and dynamic nature, tools for imaging and tracking these cells at scales spanning the whole body down to microns could help to understand their role in disease states. Here we report fluorescent and radioisotopic quantum dots (QDs) for multimodal imaging of macrophage cells

Indexed as

Quantum DotsThyroid NeoplasmsDextransHumansIodine RadioisotopesMacrophagesOptical ImagingPositron Emission Tomography Computed TomographyDextransIodine Radioisotopesinfraredmolecular imagingopticalPETphagocyte

Identifiers

PMID35107994
PMCPMC8900655
OpenAlexW4210644602

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.