Evidence map›Paper›PMID 35107785›Full record

ReviewCurrent neurology and neuroscience reports2022

Tourette Syndrome Treatment Updates: a Review and Discussion of the Current and Upcoming Literature.

Jessica Frey, Irene A Malaty

Registry-linked trialAbstract readReview
In one paragraph

Review in Current neurology and neuroscience reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06889480 (MultitArget STereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06889480 narecruitingnot on this mapstarted 2024, after this paper: background citation

MultitArget STereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome

TypeinterventionalSponsorBeijing Tiantan HospitalRan2024 to 2026Enrolled5ConditionsTourette Syndrome, Deep Brain StimulationArmsNew Target DBS, CM-DBS, Sham Stimulation
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Tourette syndrome.Nature reviews. Disease primers · 2026
    Review
  4. Subacute convexity subdural hematoma in a child with malignant Tourette syndrome: a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  5. Review
  6. Meta-anlaysis of Internet-based Behavior Therapy for Tic Disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Conservative Management of Tourette Syndrome Tics Using Intraoral Occlusal Devices: Report of Two Cases.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jessica FreyDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.ORCID 0000-0003-1699-1817
Irene A MalatyDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA. irene.malaty@neurology.ufl.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis study aims to examine the treatments currently available for Tourette syndrome (TS) and to discuss evolving therapies, spanning behavioral, pharmacologic, complementary and alternative medicine, and neuromodulation approaches. RECENT

findingsBehavioral therapies have undergone several modifications to improve accessibility, including transitioning to a virtual format which is particularly important in the current pandemic. There are several recent or ongoing pharmacologic studies that have shown promise including the selective D1 receptor antagonist ecopipam and various cannabinoid compounds. Adaptive DBS may enable the physiologic markers of tics to determine stimulation parameters and improve tic outcomes related to neuromodulation. In recent years, there has been a wealth of research across multiple treatment domains in the TS field. This review highlights exciting and new potential options for the future treatment of patients with TS.

Indexed as

Deep Brain StimulationTicsTourette SyndromeBehavior TherapyHumansCBITDeep brain stimulationNeuromodulationPharmacotherapyTicsTourette syndrome

Identifiers

PMID35107785
PMCPMC8809236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.