ArticleMagma (New York, N.Y.)2022
Oxygen saturation-dependent effects on blood transverse relaxation at low fields.
Article in Magma (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Functional magnetic resonance imaging and diffuse tensor imaging diagnostic values in central post-stroke pain.Postepy psychiatrii neurologii · 2025Review
- Multiparametric MRI: can we assess renal function differently?Clinical kidney journal · 2025Review
- Oxygen saturation-dependent effects on blood transverse relaxation at low fields.Magma (New York, N.Y.) · 2022Article
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Authors and funding
8 authors.
Funding
Abstract
objectiveBlood oxygenation can be measured using magnetic resonance using the paramagnetic effect of deoxy-haemoglobin, which decreases the [Formula: see text] relaxation time of blood. This [Formula: see text] contrast has been well characterised at the [Formula: see text] fields used in MRI (1.5 T and above). However, few studies have characterised this effect at lower magnetic fields. Here, the feasibility of blood oximetry at low field based on [Formula: see text] changes that are within a physiological relevant range is explored. This study could be used for specifying requirements for construction of a monitoring device based on low field permanent magnet systems.
methodsA continuous flow circuit was used to control parameters such as oxygen saturation and temperature in a sample of blood. It flowed through a variable field magnet, where CPMG experiments were performed to measure its [Formula: see text]. In addition, the oxygen saturation was monitored by an optical sensor for comparison with the [Formula: see text] changes.
resultsThese results show that at low [Formula: see text] fields, the change in blood [Formula: see text] due to oxygenation is small, but still detectable. The data measured at low fields are also in agreement with theoretical models for the oxy-deoxy [Formula: see text] effect.
conclusion[Formula: see text] changes in blood due to oxygenation were observed at fields as low as 0.1 T. These results suggest that low field NMR relaxometry devices around 0.3 T could be designed to detect changes in blood oxygenation.
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