Evidence map›Paper›PMID 35107655›Full record

ArticleJournal of behavioral medicine2022

Symptom burden profiles in men with advanced prostate cancer undergoing androgen deprivation therapy.

Blanca Noriega Esquives, Tae K Lee, Patricia I Moreno, Rina S Fox, Betina Yanez, Gregory E Miller, Ryne Estabrook, Mark J Begale, Sarah C Flury, Kent Perry and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of behavioral medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Blanca Noriega EsquivesDepartment of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1006, Miami, FL, 33136, USA. bsn24@med.miami.edu.
Tae K LeeDepartment of Convergence for Social Innovation, Department of Child Psychology and Education, Sungkyunkwan University, Seoul, South Korea.
Patricia I MorenoDepartment of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1006, Miami, FL, 33136, USA.
Rina S FoxCollege of Nursing, University of Arizona, Tucson, USA.
Betina YanezDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, USA.
Gregory E MillerInstitute for Policy Research and Department of Psychology, Northwestern University, Evanston, USA.
Ryne EstabrookHealth Outcomes and Behavior Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, USA.
Mark J BegaleVibrent Health, Fairfax, USA.
Sarah C FluryDepartment of Urology, Vanderbilt University School of Medicine, Nashville, USA.
Kent PerryDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, USA.
Shilajit D KunduDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, USA.
Frank J PenedoDepartment of Psychology, University of Miami, Coral Gables, USA.

Funding

Tele-based Psychosocial Intervention for Symptom Management & HRQOL in Men LivingR01CA157809 · NCI · UNIVERSITY OF MIAMI CORAL GABLES · PI PENEDO, FRANK J · 2011 to 2016
$2.9M
Improving sleep in gynecologic cancer survivorsK08CA247973 · NCI · UNIVERSITY OF ARIZONA · PI FOX, RINA S · 2021 to 2025
$926k
Patient Activation and Palliative Care among Hispanics/Latinos with Metastatic CancerK01CA258955 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MORENO, PATRICIA INGRID · 2021 to 2025
$834k
NCI NIH HHS K01 CA258955NCI NIH HHS K08 CA247973NCI NIH HHS R01 CA157809
6 · The paper itself

Abstract

To identify symptom burden profiles among men with advanced prostate cancer undergoing androgen-deprivation therapy and examine their association with baseline sociodemographic and medical characteristics and psychosocial outcomes over time. Latent profile analysis was employed to identify distinct groups based on the Expanded Prostate Index Composite and the McGill Pain Questionnaire at baseline. Psychosocial outcomes were assessed at baseline, 6- and 12-month follow-ups. Three profiles emerged: "high symptom burden," "high sexual bother," and "low symptom burden." Men with "high symptom burden" were younger and exhibited higher baseline levels of depression, stress, cancer-specific distress, and anxiety than men in the other two groups. However, men with "high symptom burden" also demonstrated improvement in these psychosocial outcomes over time. Men with advanced prostate cancer who experience multiple co-occurring symptoms demonstrate worse psychosocial adjustment. Patients with substantial symptom burden, and specifically young men, may benefit from prompt referral to supportive care services.

Indexed as

Androgen AntagonistsProstatic NeoplasmsAndrogensAnxietyHumansMaleQuality of LifeAndrogen AntagonistsAndrogensAndrogen deprivation therapyLatent profile analysisProstate cancerPsychosocial well-beingQuality of lifeSymptom burden

Identifiers

PMID35107655
PMCPMC9167233

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.