Evidence map›Paper›PMID 35107380›Full record

ArticleJournal of virology2022

Development of Recombinant Infectious Hepatitis E Virus Harboring the nanoKAZ Gene and Its Application in Drug Screening.

Putu Prathiwi Primadharsini, Shigeo Nagashima, Takashi Nishiyama, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. EIF4H and YBX1 are essential host factors for hepatitis E virus replication and pathogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Article
  6. Reporter-expressing viruses for antiviral drug discovery research.Frontiers in cellular and infection microbiology · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Putu Prathiwi PrimadharsiniDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi, Japan.ORCID 0000-0001-7401-979X
Shigeo NagashimaDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi, Japan.ORCID 0000-0001-8944-713X
Takashi NishiyamaLaboratory for Drug Target Research, Integrated Bioscience Division, Institute of Agriculture, Shinshu Universitygrid.263518.b, Nagano, Japan.ORCID 0000-0002-4496-240X
Masaharu TakahashiDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi, Japan.ORCID 0000-0001-6888-9318
Kazumoto MurataDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi, Japan.ORCID 0000-0002-3419-6297
Hiroaki OkamotoDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi, Japan.ORCID 0000-0003-0827-0964
Jichi Medical University · JPShinshu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) is a quasi-enveloped virus with a single-stranded positive-sense RNA genome belonging to the family

Indexed as

Antiviral AgentsDrug Evaluation, PreclinicalHepatitis E virusHumansVirus InternalizationVirus ReplicationAntiviral Agentsbioluminescent reporter virusdrug screeninghepatitis E virushypervariable regionmembrane-associated particlesmembrane-unassociated particlesnanoKAZ

Identifiers

PMID35107380
PMCPMC8941883
OpenAlexW4210581494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.