ArticleEndocrine connections2022
Fatigue and quality of life among thyroid cancer survivors without persistent or recurrent disease.
Article in Endocrine connections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- The 2024 revised clinical guidelines on the management of thyroid tumors by the Japan Association of Endocrine Surgery.Endocrine journal · 2025Guideline
- Symptom clusters and quality of life among patients with thyroid cancer during early survivorship: a national multicenter cross-sectional study.The oncologist · 2026Article
- Current non-pharmacological practices for cancer-related fatigue in oncology rehabilitation: results of a national provider survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Symptom clusters and contemporaneous symptom network analysis at discharge in patients with differentiated thyroid cancer after thyroidectomy.Endocrine · 2026Article
- Health-related quality of life and predictors in differentiated thyroid cancer patients during the transitional period: A Cross-sectional study.Endocrine · 2026Article
- Serum 25-hydroxyvitamin D and health-related quality of life in patients with papillary thyroid carcinoma: a prospective cohort study.Frontiers in nutrition · 2026Article
- Longitudinal relationships of malnutrition risk, sleep disturbance, and fear of cancer recurrence in thyroid cancer patients: a cross-lagged panel model.Frontiers in nutrition · 2026Article
- Factors Associated with Sleep Disruption and Fatigue in Thyroid Cancer Survivors.Current oncology (Toronto, Ont.) · 2025Article
- Sleep disorders in patients with differentiated thyroid cancer: a case-control study.Endocrine · 2025Article
- Thyroid disease in ageing populations.Endocrine connections · 2025Article
- Article
- Health-related quality of life and radioiodine therapy in thyroid cancer patients: a before-and-after study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Influence of transcatheter arterial embolization on symptom distress and fatigue in liver cancer patients.World journal of gastrointestinal oncology · 2024Article
- Association of Anxiety and Depressive Symptoms with Thyroid Hormone Concentrations in Patients with Primary Bone Tumors.Endocrine, metabolic & immune disorders drug targets · 2024Article
- Effect of Psychological Intervention on Differentiated Thyroid Cancer Patients in the Treatment with Radioactive Iodine.Patient preference and adherence · 2023Article
- Quality of Life of Survivors of Thyroid Cancer Is Not Inferior to That in Subjects without Cancer: Long-Term after Over 5 Years.Endocrinology and metabolism (Seoul, Korea) · 2022Article
- Health-related quality of life in long-term differentiated thyroid cancer survivors: A cross-sectional Tunisian-based study.Frontiers in endocrinology · 2022Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer-related fatigue is one of the most important issues for patients, but research on this topic is sparse. This study aimed to determine the prevalence of fatigue in postoperative patients with papillary thyroid carcinoma (PTC) and to identify the clinical features associated with fatigue.
methodsWe conducted a cross-sectional study on 292 thyroid cancer survivors. Fatigue and quality of life were the study outcomes, measured using the Cancer Fatigue Scale (CFS) and the SF-36 version 2.0. Furthermore, correlations of demographic characteristics and hormonal data with the CFS scores were assessed by univariable and multivariable analyses.
resultsThe prevalence of fatigue was 41.8% (95% CI: 36.1, 47.5). The CFS score was significantly correlated with the free T3 level (Pearson's r = -0.123, 95% CI: -0.234, -0.008). Multiple regression analysis revealed that the free T3 level and having a job were significant predictors of the CFS score, with unstandardized regression coefficients of -2.52 (95% CI: -4.94, -0.09) and 2.85 (95% CI: 0.49, 5.20), respectively. The median Z-scores were negative for General Health (-0.28) and Vitality (-0.15) subscales of the SF-36. The CFS score was a significant predictor of summary scores of the SF-36. The free T3 level was significantly associated with the physical component summary score with an unstandardized coefficient of 3.20 (95% CI: 0.77, 5.63).
conclusionsFatigue was prevalent and associated with poor quality of life among PTC survivors. Thyroid functional status, particularly the level of free T3, may be worth to be considered in alleviating the burden.
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