Evidence map›Paper›PMID 35107032›Full record

ReviewAmerican journal of physiology. Gastrointestinal and liver physiology2022

The therapeutic potential of exosomes derived from different cell sources in liver diseases.

Yun Pan, Wei-Feng Tan, Mu-Qing Yang, Ji-Yu Li, David A Geller

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Gastrointestinal and liver physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  5. Specific Binding of Alzheimer's Aβ Peptides to Extracellular Vesicles.International journal of molecular sciences · 2024
    Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Yun PanColorectal Cancer Center, Tenth People's Hospital of Tongji University, Tongji University School of Medicine, Shanghai, People's Republic of China.ORCID 0000-0001-5470-1206
Wei-Feng TanDepartment of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Mu-Qing YangDepartment of General Surgery, Tenth People's Hospital of Tongji University, Tongji University, Shanghai, People's Republic of China.
Ji-Yu LiDepartment of General Surgery, Tenth People's Hospital of Tongji University, Tongji University, Shanghai, People's Republic of China.
David A GellerDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Tongji University · CNShanghai Jiao Tong University · CNUniversity of Pittsburgh Medical Center · US

Funding

Pittsburgh Liver Research CenterP30DK120531 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAVID A GELLER · 2019 to 2026
$10.9M
NIDDK NIH HHS P30 DK120531
6 · The paper itself

Abstract

Exosomes are small nanovesicles with a size of approximately 40-120 nm that are secreted from cells. They are involved in the regulation of cell homeostasis and mediate intercellular communication. In addition, they carry proteins, nucleic acids, and lipids that regulate the biological activity of receptor cells. Recent studies have shown that exosomes perform important functions in liver diseases. This review will focus on liver diseases (drug-induced liver injury, hepatic ischemia-reperfusion injury, liver fibrosis, acute liver failure, and hepatocellular carcinoma) and summarize the therapeutic potential of exosomes from different cell sources in liver disease.

Indexed as

Carcinoma, HepatocellularExosomesLiver NeoplasmsHumansLiver Cirrhosisexosomesliver diseaseroletherapeutic potential

Identifiers

PMID35107032
PMCPMC8917924
OpenAlexW4210537464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.