Evidence map›Paper›PMID 35106889›Full record

ReviewBiological reviews of the Cambridge Philosophical Society2022

The revolutionary developmental biology of Wilhelm His, Sr.

Michael K Richardson, Gerhard Keuck

Abstract readReview
In one paragraph

Review in Biological reviews of the Cambridge Philosophical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Network-Associated Mechanotransduction in Health and Disease.Results and problems in cell differentiation · 2026
    Review
  3. Review
  4. Article
  5. Collective behavior and self-organization in neural rosette morphogenesis.Frontiers in cell and developmental biology · 2023
    Review
  6. Theories, laws, and models in evo-devo.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael K RichardsonInstitute of Biology, University of Leiden, Sylvius Laboratory, Sylviusweg 72, Leiden, 2333 BE, The Netherlands.ORCID 0000-0003-1222-8101
Gerhard KeuckGeißspitzweg 8, Frankfurt, 65929, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Swiss-born embryologist Wilhelm His, Sr. (1831-1904) was the first scientist to study embryos using paraffin histology, serial sectioning and three-dimensional modelling. With these techniques, His made many important discoveries in vertebrate embryology and developmental neurobiology, earning him two Nobel Prize nominations. He also developed several theories of mechanical and evolutionary developmental biology. His argued that adult form is determined by the differential growth of developmental primordia. Furthermore, he suggested that changes in the growth parameters of those primordia are responsible for generating new phenotypes during evolution. His developed these theories in his book 'Our Bodily Form' (Unsere Körperform). Here, we review His's work with special emphasis on its potential importance to the disciplines of evolutionary developmental biology (evo-devo) and mechanobiology.

Indexed as

Developmental BiologyEmbryonic DevelopmentAnimalsBiological EvolutionMalePhenotypeallometryEntwicklungsmechanikevo-devoevolution and developmentgastrulationgerm layermechanobiologymorphogenesisWilhelm His

Identifiers

PMID35106889
PMCPMC9304566

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.