Evidence map›Paper›PMID 35106643›Full record

ArticleArchives of gynecology and obstetrics2022

The web-based application "QUiPP v.2" for the prediction of preterm birth in symptomatic women is not yet ready for worldwide clinical use: ten reflections on development, validation and use.

Isabelle Dehaene, Johan Steen, Gilles Vandewiele, Kristien Roelens, Johan Decruyenaere

Open access · bronzeAbstract readLetter
In one paragraph

Article in Archives of gynecology and obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Isabelle DehaeneObstetrics and Gynaecology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium. isabelle.dehaene@ugent.be.ORCID 0000-0002-4826-6946
Johan SteenDepartment of Internal Medicine and Paediatrics, Renal Division, Ghent University, Ghent, Belgium.ORCID 0000-0002-5968-6401
Gilles VandewieleIDLab, Ghent University-IMEC, Ghent, Belgium.ORCID 0000-0001-9531-0623
Kristien RoelensObstetrics and Gynaecology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.ORCID 0000-0003-0973-7554
Johan DecruyenaereDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0002-3655-4318
Ghent University Hospital · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this correspondence, we highlight general and domain-specific caveats in the development and validation of prediction models.

methodsDevelopment and use of the "QUiPP" application, a tool for preterm birth prediction which is supported by the United Kingdom National Health Service, is scrutinised and commented on.

resultsWe highlight and elaborate ten points which may be perceived to be unclear or potentially misleading.

conclusionWhile the QUiPP application has high potential, it lacks transparency (on certain aspects related to model development) and proper validation. This precludes transportability to settings with other treatment policies and to other countries where the app has been made publicly available.

Indexed as

Premature BirthCervical Length MeasurementCervix UteriFemaleFibronectinsHumansInfant, NewbornInternetPredictive Value of TestsPregnancyProspective StudiesState MedicineFibronectinsCervical lengtheHealthFibronectinPreterm birth predictionQUiPP

Identifiers

PMID35106643
PMCPMC8807143
OpenAlexW4210320121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.