Evidence map›Paper›PMID 35106562›Full record

ArticleInteractive cardiovascular and thoracic surgery2022

Impact of the HeartMate 3 continuous-flow left ventricular assist device in patients with small body size.

Kohei Tonai, Satsuki Fukushima, Naoki Tadokoro, Satoshi Kainuma, Naonori Kawamoto, Takashi Kakuta, Ayumi Koga-Ikuta, Takuya Watanabe, Osamu Seguchi, Yasumasa Tsukamoto and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Kohei TonaiDepartment of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.ORCID 0000-0003-3410-859X
Satsuki FukushimaDepartment of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.ORCID 0000-0002-9481-8860
Naoki TadokoroDepartment of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.ORCID 0000-0002-4658-852X
Satoshi KainumaDepartment of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Naonori KawamotoDepartment of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Takashi KakutaDepartment of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Ayumi Koga-IkutaDepartment of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Takuya WatanabeDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Osamu SeguchiDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Yasumasa TsukamotoDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Norihide FukushimaDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Tomoyuki FujitaDepartment of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.ORCID 0000-0003-3023-5014
National Cerebral and Cardiovascular Center · JP

Funding

Japan Cardiovascular Research Foundation
6 · The paper itself

Abstract

objectivesLimited data are available for use of the HeartMate 3 (HM 3) left ventricular assist device in patients with a small body surface area (BSA). Because the HM 3 is currently the sole device available worldwide, we conducted a single-centre retrospective study of patients with a small BSA (<1.5 m2) who underwent HM 3 implantation to better understand the operative and postoperative management.

methodsThis study enrolled 64 consecutive patients who had undergone HM 3 implantation from August 2018 to July 2021. The patients were divided into 2 groups based on their BSA before the operation: BSA of <1.5 m2 (small BSA group, n = 18) and BSA of ≥1.5 m2 (regular BSA group, n = 46). The primary study endpoint was survival free of events such as disabling stroke and pump failure. The secondary endpoint was the frequency of adverse events.

resultsThe average BSA was 1.38 m2 in the small BSA group. The overall event-free survival rate at 12 months was 100% and 86.7% in the small BSA group and regular BSA group, respectively, and no significant difference was found between the 2 groups (log-rank P = 0.2). The number of cumulative adverse events of death, stroke of any severity, driveline infection, pump infection, ventricular arrhythmia, gastrointestinal Haemorrhage and pump failure was similar between the 2 groups.

conclusionsThe HM 3 was safely implanted in patients with a small BSA, and postoperative outcomes were acceptable regardless of BSA. However, further research is needed to confirm the indications for HM 3 implantation in even smaller patients.

Indexed as

Heart-Assist DevicesHeart FailureStrokeBody SizeHumansRetrospective StudiesSurvival RateTreatment OutcomeBody surface areaHeartMate 3Small patientsVentricular assist device

Identifiers

PMID35106562
PMCPMC9070502
OpenAlexW4210701607

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.