Evidence map›Paper›PMID 35106455›Full record

ArticleiScience2022

A preliminary model of football-related neural stress that integrates metabolomics with transcriptomics and virtual reality.

Nicole L Vike, Sumra Bari, Khrystyna Stetsiv, Alexa Walter, Sharlene Newman, Keisuke Kawata, Jeffrey J Bazarian, Zoran Martinovich, Eric A Nauman, Thomas M Talavage and 3 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Early changes in urineMetabolomics : Official journal of the Metabolomic Society · 2025
    Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Nicole L VikeWarren Wright Adolescent Center Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Sumra BariWarren Wright Adolescent Center Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Khrystyna StetsivWarren Wright Adolescent Center Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Alexa WalterDepartment of Kinesiology, Pennsylvania State University, University Park, PA 16801, USA.
Sharlene NewmanDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA.
Keisuke KawataDepartment of Kinesiology, School of Public Health-Bloomington, Indiana University, Bloomington, IN 47405, USA.
Jeffrey J BazarianDepartment of Emergency Medicine, University of Rochester, Rochester, NY 14627, USA.
Zoran MartinovichWarren Wright Adolescent Center Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Eric A NaumanWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Thomas M TalavageWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Linda PapaDepartment of Emergency Medicine, Orlando Regional Medical Center, Orlando, FL 32806, USA.
Semyon M SlobounovDepartment of Kinesiology, Pennsylvania State University, University Park, PA 16801, USA.
Hans C BreiterWarren Wright Adolescent Center Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Northwestern University · USIndiana University Bloomington · USPennsylvania State University · USPurdue University West Lafayette · USOrlando Regional Medical Center · USUniversity of Rochester · US

Funding

Biomarkers of Mild and Moderate Traumatic Brain InjuryR01NS057676 · NINDS · ORLANDO REGIONAL HEALTHCARE SYSTEM, INC. · PI PAPA, LINDA · 2008 to 2022
$5.8M
NINDS NIH HHS R01 NS057676
6 · The paper itself

Abstract

Research suggests contact sports affect neurological health. This study used permutation-based mediation statistics to integrate measures of metabolomics, neuroinflammatory miRNAs, and virtual reality (VR)-based motor control to investigate multi-scale relationships across a season of collegiate American football. Fourteen significant mediations (six pre-season, eight across-season) were observed where metabolites

Indexed as

Computer graphicsMetabolomicsTranscriptomicsTrauma

Identifiers

PMID35106455
PMCPMC8786649
OpenAlexW4200042155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.