Evidence map›Paper›PMID 35106333›Full record

ArticleThe archives of bone and joint surgery2021

Periprosthetic Joint Infection after Endoprosthetic Reconstruction: Saving the Limb-Salvage.

Wylie Lopez, Kayoumars Azizpour, Kevin Raskin, Santiago Lozano-Calderón

Open access · greenAbstract read
In one paragraph

Article in The archives of bone and joint surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Wylie LopezDepartment of Orthopaedic Surgery, Massachusetts General Hospital, MA, USA.
Kayoumars AzizpourHarvard Medical School, Boston MA, USA.
Kevin RaskinDepartment of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
Santiago Lozano-CalderónMassachusetts General Hospital, Boston, MA, USA.
Massachusetts General Hospital · USHarvard University · USLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study evaluates mega-endoprosthetic survival after revision for periprosthetic joint infection (PJI) and two-staged reconstruction using a cement spacer. Mega-endoprosthetics offer patients an important treatment option for limb salvage. However, PJI is a devastating complication which affects between 2-10% of patients. It commonly results in revisions, amputation, and sometimes death. Literature in terms of success rates, limb salvage and Megaprostheses survival after revision for infection is limited. We present here our experience and the impact of length of the spacer in prostheses survival.

methodsA retrospective chart review was implemented using Fisher's exact test for categorical data and the Kaplan-Meier method for prosthesis survival. Patient information was acquired through our institution's electronic medical records. Variables such as diagnosis, complications, length of cement spacer, and number of surgeries were recorded. We analyzed spacer length and prosthesis survival based on these variables.

resultsFisher's Exact test showed no correlation between length of spacer and amount of repeat surgery (

conclusionThese data suggest long-term viability of mega-endoprostheses after two-stage revision despite a high complication rate.

Indexed as

Limb salvageMega-endoprosthesisPeriprosthetic joint infectionTwo-stage revision

Identifiers

PMID35106333
PMCPMC8765206
OpenAlexW3135766976

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.