ReviewThe archives of bone and joint surgery2021
Staged Bilateral Total Knee Arthroplasty: When Should the Second Knee be Replaced?
Review in The archives of bone and joint surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Association of interstage timing and prior surgical response with outcomes following staged bilateral total knee arthroplasty: A retrospective cohort study.Journal of experimental orthopaedics · 2026Article
- The impact of past surgical history on postoperative outcomes following primary total joint arthroplasty: a retrospective study.Annals of joint · 2026Article
- Second-Stage Knee Pain is Not Increased After Staged Bilateral Total Knee Arthroplasty: A Retrospective Linear Mixed-Effects Analysis of 72-Hour Postoperative Pain.Orthopedic research and reviews · 2026Article
- Bilateral Total Ankle Arthroplasty in a Hemophiliac Patient: A Case Report and Literature Review.Journal of clinical medicine · 2025Article
- Comparing 90-day morbidity and mortality after unilateral versus simultaneous bilateral total knee arthroplasty in a Saudi population. A retrospective cohort study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Optimal timing for the second surgery in staged bilateral total knee arthroplasty: a patient-determined interval approach.BMC surgery · 2025Article
- Regional Differences in Primary Total Knee Arthroplasty Utilization, Physician Reimbursement, and Patient Characteristics.Arthroplasty today · 2024Article
- Hybrid Cementation Technique Using the New Modular System for Aseptic Knee Arthroplasty Revision Surgery.The archives of bone and joint surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBilateral total knee arthroplasty (BTKA) under the same anesthesia (simultaneous) or staged are options for patients with end-stage arthritis of the knee that carries advantages and limitations. Not all patients are candidates for simultaneous BTKA, and therefore, surgeons prefer to stage the two TKAs. The optimal safe interval between two TKAs is not known. The present systematic review aimed to determine the optimal time interval between the two stages of BTKA.
methodsPubmed and Scopus databases were searched to identify publications from January 1979 to November 2017 in English that compared the outcomes of staged BTKA performed using various time intervals between the two TKAs. Data on systemic and local complications following staged BTKA were extracted, and the pooled data were analyzed to adjust for age.
resultsIn total, 23 studies that enrolled 117,090 patients undergoing staged BTKA were included in this systematic review. A significant increase was observed in the incidence of myocardial infarction (OR=8.4 and 8.32), other cardiac complications (OR=17.71 and 18.18), deep vein thrombosis (OR=4.72 and 4.89), pneumonia (OR=3.37 and 3.45), and knee revision (OR=3.73 and 4.14) in patients undergoing the second TKA within 30 days or 90 days of the first TKA. However, the replacement of the second knee within this time interval was associated with a significantly lower risk of pulmonary embolism (OR=0.145 and 0.128), superficial (OR=0.14 and 0.79) and deep knee infection (OR=0.0 and 0.0), as well as vascular complications (OR=0.0 and 0.42).
conclusionTime interval of less than 30 or 90 days between two TKAs performed in patients with BTKA was associated with a higher risk of systematic complications. However, the shorter time intervals between the two TKA may reduce the risk of other complications. This information may help surgeons' council patients better when deciding on the optimal time interval between two TKAs.
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Registered trials
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