ArticleEFSA journal. European Food Safety Authority2022
Scientific Opinion on development needs for the allergenicity and protein safety assessment of food and feed products derived from biotechnology.
Article in EFSA journal. European Food Safety Authority, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 70 citations in OpenAlex.
- Assessment of Allergenic Potential for Cross-Reactivity of Olive (Food science & nutrition · 2026Article
- Application of new approach methods (NAMs) in food safety with considerations for new proteins.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2026Review
- Prediction of plant food allergens using protein embeddings.Bioinformatics advances · 2026Article
- Assessment of genetically modified soybean MON 94637 (application GMFF-2023-21116).EFSA journal. European Food Safety Authority · 2025Article
- New developments in biotechnology applied to animals: An assessment of the adequacy and sufficiency of current EFSA guidance for animal risk assessment.EFSA journal. European Food Safety Authority · 2025Article
- Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae.Journal of applied toxicology : JAT · 2025Article
- Traditional and Emerging Physical Processing Technologies: Applications and Challenges in Allergen Control of Animal and Plant Proteins.Comprehensive reviews in food science and food safety · 2025Review
- Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration.International journal of extreme manufacturing · 2025Review
- Refining the safety assessment of newly expressed proteins in GMOs.Frontiers in toxicology · 2025Article
- Genetically modified crops and sustainable development: navigating challenges and opportunities.Food science and biotechnology · 2025Review
- IntegratingCurrent research in food science · 2025Article
- Enhancing allergenicity risk assessment for novel foods in the EU: insights from the updated EFSA guidance - requirements, knowledge gaps and research needs.Frontiers in toxicology · 2025Review
- Duckweeds as edible vaccines in the animal farming industry.3 Biotech · 2024Review
- Guidance on the scientific requirements for an application for authorisation of a novel food in the context of Regulation (EU) 2015/2283.EFSA journal. European Food Safety Authority · 2024Article
- New developments in biotechnology applied to microorganisms.EFSA journal. European Food Safety Authority · 2024Article
- The Potential Harmful Effects of Genetically Engineered Microorganisms (GEMs) on the Intestinal Microbiome and Public Health.Microorganisms · 2024Review
- Research gaps and future needs for allergen prediction in food safety.Frontiers in allergy · 2024Review
- Molecular farming navigates a complex regulatory landscape.Frontiers in plant science · 2024Article
- Green Biologics: Harnessing the Power of Plants to Produce Pharmaceuticals.International journal of molecular sciences · 2023Review
- A Food Matrix Triggers a Similar Allergic Immune Response in BALB/c Mice Sensitized with Native, Denatured, and Digested Ovalbumin.Life (Basel, Switzerland) · 2023Article
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Authors and funding
18 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This Scientific Opinion addresses the formulation of specific development needs, including research requirements for allergenicity assessment and protein safety, in general, which is urgently needed in a world that demands more sustainable food systems. Current allergenicity risk assessment strategies are based on the principles and guidelines of the Codex Alimentarius for the safety assessment of foods derived from 'modern' biotechnology initially published in 2003. The core approach for the safety assessment is based on a 'weight-of-evidence' approach because no single piece of information or experimental method provides sufficient evidence to predict allergenicity. Although the Codex Alimentarius and EFSA guidance documents successfully addressed allergenicity assessments of single/stacked event GM applications, experience gained and new developments in the field call for a modernisation of some key elements of the risk assessment. These should include the consideration of clinical relevance, route of exposure and potential threshold values of food allergens, the update of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.