Evidence map›Paper›PMID 35105933›Full record

ArticleScientific reports2022

Tetrahydroxy stilbene glycoside attenuates endothelial cell premature senescence induced by H

Lixuan Zhang, Yan Guo, Shennan Shi, Yani Zhuge, Nipi Chen, Zhishan Ding, Bo Jin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. miR-96-5p expression is sufficient to induce and maintain the senescent cell fate in the absence of stress.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lixuan Zhang *College of Life Science, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China.
Yan Guo *College of Basic Medicine, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China.
Shennan ShiCollege of Life Science, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China.
Yani ZhugeCollege of Life Science, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China.
Nipi ChenCollege of Life Science, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China.
Zhishan DingSchool of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China. dzszjtcm@163.com.
Bo JinCollege of Life Science, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China. jinbo@zcmu.edu.cn.
Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have demonstrated that endothelial cell senescence plays a decisive role in the development and progression of cardiovascular diseases (CVD). Our previous results confirmed that Tetrahydroxy stilbene glycoside (TSG) can alleviate the human umbilical vein endothelial cells (HUVECs) senescence induced by H

Indexed as

CarbazolesCells, CulturedCellular SenescenceGene Knockdown TechniquesGlucosidesHumansHuman Umbilical Vein Endothelial CellsHydrogen PeroxideMicroRNAsSignal TransductionSirtuin 1StilbenesTransfection2',3',4',5'-tetrahydroxystilbene-2-O-beta-D-glucoside6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamideCarbazolesGlucosidesHydrogen PeroxideMicroRNAsMIRN34 microRNA, humanSIRT1 protein, humanSirtuin 1Stilbenes

Identifiers

PMID35105933
PMCPMC8807705
OpenAlexW4210787700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.