Evidence map›Paper›PMID 35105730›Full record

ArticleStroke and vascular neurology2022

Thrombolysis of stroke mimics via telestroke.

Vivien H Lee, Ravyn Howell, Randheer Yadav, Sharon Heaton, Karen L Wiles, Sushil Lakhani

Open access · goldAbstract read
In one paragraph

Article in Stroke and vascular neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Global stroke statistics 2023: Availability of reperfusion services around the world.International journal of stroke : official journal of the International Stroke Society · 2024
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vivien H LeeNeurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA vivien.lee@osumc.edu.ORCID 0000-0002-8615-198X
Ravyn HowellNeurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Randheer YadavNeurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Sharon HeatonNeurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Karen L WilesNeurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Sushil LakhaniNeurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
The Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rate of intravenous tissue plasminogen activator (IVtPA) administered to stroke mimics (SM) occurs in 24%-44% of telestroke series.

methodsWe reviewed 270 suspected acute ischaemic stroke (AIS) patients who were evaluated by telestroke and received IVtPA from 1 July 2016 to 30 September 2017 at our academic comprehensive stroke centre.

resultsAmong 270 AIS patients who received IVtPA via telestroke, 64 (23.7%) were diagnosed with SM. Compared with patients who had a stroke, the SM group was younger (mean age 56.4 vs 68.2, p<0.0001), more likely to be female (60.9% vs 45.6%, p=0.0324) and had longer door-to-needle times (85.3 vs 69.9, p=0.0008). The most common SM diagnoses were migraine 26 (40.6%), conversion disorder 12 (18.8%), encephalopathy 7 (10.9%) and unmasking (9.4%). Among the SM, migraine and conversion disorder were younger compared with the other subgroups (p<0.001). Functional exam elements were noted more frequently in conversion disorder (66.7%) and migraine (34.6%), but rare in other diagnoses (p=0.006). Among the SM, 23 (35.9%) had a history of a prior similar episodes, and 15 (23.4%) had a history of more than 5 spells.

conclusionsIn our telestroke programme, 23.7% of those administered thrombolysis had a final diagnosis of SM.

Indexed as

Brain IschemiaMigraine DisordersStrokeTelemedicineAgedFemaleFibrinolytic AgentsHumansMaleMiddle AgedThrombolytic TherapyTissue Plasminogen ActivatorFibrinolytic AgentsTissue Plasminogen Activatorstrokethrombolysis

Identifiers

PMID35105730
PMCPMC9240458
OpenAlexW4210812092

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.