Evidence map›Paper›PMID 35105715›Full record

ArticleThe Journal of rheumatology2022

Profiling Behavioral and Psychological Symptoms in Children Undergoing Treatment for Spondyloarthritis and Polyarthritis.

Anne McHugh, Avis Chan, Carolyn Herrera, Jennifer M Park, Imelda Balboni, Dana Gerstbacher, Joyce J Hsu, Tzielan Lee, Margo Thienemann, Jennifer Frankovich

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Anne McHughA. McHugh, MD, Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, and Division of Rheumatology, Department of Pediatrics, Wright State University Boonshoft School of Medicine, Dayton, Ohio.ORCID 0000-0002-3657-7261
Avis ChanA. Chan, MD, MS, C. Herrera, BS, I. Balboni MD, PhD, D. Gerstbacher, MD, J.J. Hsu, MD, MS, T. Lee, MD, J. Frankovich, MD, MS, Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.ORCID 0000-0002-6796-4280
Carolyn HerreraA. Chan, MD, MS, C. Herrera, BS, I. Balboni MD, PhD, D. Gerstbacher, MD, J.J. Hsu, MD, MS, T. Lee, MD, J. Frankovich, MD, MS, Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Jennifer M ParkJ.M. Park, PhD, Rogers Behavioral Health San Francisco, Walnut Creek, California.
Imelda BalboniA. Chan, MD, MS, C. Herrera, BS, I. Balboni MD, PhD, D. Gerstbacher, MD, J.J. Hsu, MD, MS, T. Lee, MD, J. Frankovich, MD, MS, Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Dana GerstbacherA. Chan, MD, MS, C. Herrera, BS, I. Balboni MD, PhD, D. Gerstbacher, MD, J.J. Hsu, MD, MS, T. Lee, MD, J. Frankovich, MD, MS, Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.ORCID 0000-0001-7135-6766
Joyce J HsuA. Chan, MD, MS, C. Herrera, BS, I. Balboni MD, PhD, D. Gerstbacher, MD, J.J. Hsu, MD, MS, T. Lee, MD, J. Frankovich, MD, MS, Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Tzielan LeeA. Chan, MD, MS, C. Herrera, BS, I. Balboni MD, PhD, D. Gerstbacher, MD, J.J. Hsu, MD, MS, T. Lee, MD, J. Frankovich, MD, MS, Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Margo ThienemannM. Thienemann, MD, Division of Child and Adolescent Psychiatry and Child Development, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, California, USA.ORCID 0000-0002-4952-4775
Jennifer FrankovichA. Chan, MD, MS, C. Herrera, BS, I. Balboni MD, PhD, D. Gerstbacher, MD, J.J. Hsu, MD, MS, T. Lee, MD, J. Frankovich, MD, MS, Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.ORCID 0000-0001-7356-5617
Stanford University · USPalo Alto University · USRogers Behavioral Health · USWright State University · US

Funding

Training Program in Adult and Pediatric RheumatologyT32AR050942 · NIAMS · STANFORD UNIVERSITY · PI LEWIS, DAVID BRAM, ROBINSON, WILLIAM H · 2005 to 2025
$6.6M
NIAMS NIH HHS T32 AR050942
6 · The paper itself

Abstract

objectiveFew studies examine psychopathology in different juvenile idiopathic arthritis (JIA) subtypes and disease activity states. We aimed to (1) evaluate emotional and behavioral symptoms in children with juvenile spondyloarthritis (SpA) and polyarticular arthritis (PolyA) as compared to a national normative population using the Child Behavior Checklist (CBCL), and (2) evaluate the relationship between CBCL scores and disease activity.

methodsPatients with JIA aged 6-17 years with SpA or PolyA were recruited from our pediatric rheumatology clinic from April 2018 to April 2019 and the CBCL and clinical Juvenile Arthritis Disease Activity Score in 10 joints (cJADAS10) were completed. Primary outcome measures were CBCL total competence, internalizing, externalizing, and total problems raw scores. We compared outcomes from each group to national CBCL normative data. To investigate the relationship between CBCL scores and disease activity, we ran a generalized linear regression model for all patients with arthritis with cJADAS10 as the main predictor.

resultsThere were 111 patients and 1753 healthy controls (HCs). Compared to HCs, patients with SpA or PolyA had worse total competence and internalizing scores. Higher cJADAS10 scores were associated with worse total competence, worse internalizing, and higher total problems scores. Most of these differences reached statistical significance (

conclusionOur study shows that patients with SpA and PolyA with more active disease have worse psychological functioning in activities, school, and social arenas, and more internalized emotional disturbances, suggesting the need for regular mental health screening by rheumatologists.

Indexed as

Arthritis, JuvenileChild Behavior DisordersSpondylarthritisAffective SymptomsChildEmotionsHumansbehaviorpediatric rheumatologypolyarthritispsychologicspondyloarthritis

Identifiers

PMID35105715
PMCPMC9534268
OpenAlexW4210578158

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.