Evidence map›Paper›PMID 35105680›Full record

ArticleClinical medicine (London, England)2022

COVID-19 infection causing residual gastrointestinal symptoms - a single UK centre case series.

Joseph Cooney, Priscilla Appiahene, Ross Findlay, Lulia Al-Hillawi, Khizar Rafique, William Laband, Benjamin Shandro, Andrew Poullis

Open access · diamondAbstract read
In one paragraph

Article in Clinical medicine (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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  13. Post-COVID-19 irritable bowel syndrome.Neurogastroenterology and motility · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joseph CooneySt George's University Hospitals NHS Foundation Trust, London, UK josephcooney@doctors.org.uk.
Priscilla AppiaheneSt George's University Hospitals NHS Foundation Trust, London, UK.
Ross FindlaySt George's University Hospitals NHS Foundation Trust, London, UK.
Lulia Al-HillawiSt George's University Hospitals NHS Foundation Trust, London, UK.
Khizar RafiqueSt George's University Hospitals NHS Foundation Trust, London, UK.
William LabandSt George's University Hospitals NHS Foundation Trust, London, UK.
Benjamin ShandroSt George's University Hospitals NHS Foundation Trust, London, UK.
Andrew PoullisSt George's University Hospitals NHS Foundation Trust, London, UK.
St George’s University Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although COVID-19 was first recognised as an acute respiratory illness, extra-pulmonary manifestations are increasingly being recognised. Acute gastrointestinal side effects have been well reported with COVID-19 infection and are estimated to affect around 17% of patients. With COVID-19 still being a relatively new illness, the chronic gastrointestinal symptoms are less well characterised. Post-infectious irritable bowel syndrome (IBS) can occur following bacterial and viral infections, and with ACE-2 receptors being shown to be present in the gastrointestinal tract and SARS-Cov-2 RNA being present in stool, SARS-CoV-2 is now appreciated as an enteric pathogen. In our study, we survey acute and chronic gastrointestinal symptoms after COVID-19 infection. We have conducted one of the few UK studies on gastrointestinal symptoms, with the longest follow-up duration of 6 months. We have found that gastrointestinal symptoms are common at 6 months, affecting 43.8% of our patients. Further research is needed to explore whether this represents a new post-COVID-19 IBS, which has not

Indexed as

COVID-19Gastrointestinal TractHumansRNA, ViralSARS-CoV-2United KingdomRNA, ViralCOVID-19enteric infectionirritable bowel syndrome

Identifiers

PMID35105680
PMCPMC8966828
OpenAlexW4210471375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.