Evidence map›Paper›PMID 35105608›Full record

ArticleBMJ open2022

Time series analysis of the incidence of acute upper respiratory tract infections, COVID-19 and the use of antibiotics in Finland during the COVID-19 epidemic: a cohort study of 833 444 patients.

Oskar Niemenoja, Ara Taalas, Simo Taimela, Petri Bono, Pentti Huovinen, Sari Riihijärvi

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Oskar NiemenojaTerveystalo Healthcare, Helsinki, Finland.ORCID 0000-0003-1809-0051
Ara TaalasTerveystalo Healthcare, Helsinki, Finland.
Simo TaimelaTerveystalo Healthcare, Helsinki, Finland.ORCID 0000-0001-6755-2983
Petri BonoTerveystalo Healthcare, Helsinki, Finland.
Pentti HuovinenMedical Microbiology and Immunoloy, University of Turku, Turku, Finland.
Sari RiihijärviTerveystalo Healthcare, Helsinki, Finland sari.riihijarvi@icloud.com.ORCID 0000-0001-8547-0252
University of Helsinki · FIEtelä-Karjalan sosiaali ja terveyspiiri · FIUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the trajectories of acute upper respiratory tract infections (URTIs), COVID-19, and the use of antibiotics in Finland during the COVID-19 epidemic.

designPopulation-based cohort study.

settingElectronic medical records from a nationwide healthcare chain in Finland.

participants833 444 patients from a cohort of 1 970 013 Finns who had used medical services between 2017 and 2020.

main outcome measuresNumber of weekly patients of acute URTIs, COVID-19, and the prescribed number of antibiotics in Finland between 6 January 2020 and 21 June 2020. We estimated the respective expected numbers from 1 March 2020 onward using autoregressive integrated moving average model from 1 January 2017 to 1 March 2020. We assessed the public interest in COVID-19 by collecting Google search trend frequencies.

resultsThere was a rapid increase in COVID-related internet searches between weeks 10 and 12. At the same time, there was a 106% increase in diagnoses of acute URTIs, from 410 per 100 000 inhabitants to 845 per 100 000. The first COVID-19 cases were diagnosed on week 11. Prescriptions for URTI-related antibiotics declined by 71% (403 per 100 000 to 117 per 100 000) between weeks 11 and 15 while no relevant change took place in prescriptions of antibiotics for urinary tract infections.

conclusionsAt the beginning of the epidemic, many people contacted healthcare professionals with relatively mild symptoms, as indicated by the reduced rate of URTI-antibiotics prescriptions. Our findings indicate that health service providers should be prepared for rapid variations in service demand. Securing access of true COVID-19 patients to proper diagnostics, care and isolation measures may help in preventing the spread of the disease.

Indexed as

COVID-19Respiratory Tract InfectionsAnti-Bacterial AgentsCohort StudiesFinlandHumansIncidenceSARS-CoV-2Time FactorsAnti-Bacterial AgentsCOVID-19epidemiologyrespiratory infections

Identifiers

PMID35105608
PMCPMC8804308
OpenAlexW4210735115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.