Evidence map›Paper›PMID 35105348›Full record

ArticleWorld journal of surgical oncology2022

Prognostic usefulness of a modified risk model for solitary fibrous tumor that includes the Ki-67 labeling index.

Shintaro Sugita, Keiko Segawa, Noriaki Kikuchi, Tomoko Takenami, Tomomi Kido, Makoto Emori, Yukinori Akiyama, Kohichi Takada, Shiro Hinotsu, Tadashi Hasegawa

Abstract read
In one paragraph

Article in World journal of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shintaro SugitaDepartment of Surgical Pathology, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Keiko SegawaDepartment of Surgical Pathology, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Noriaki KikuchiDepartment of Surgical Pathology, Sunagawa City Medical Center, Sunagawa, Hokkaido, 073-0196, Japan.
Tomoko TakenamiDepartment of Surgical Pathology, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Tomomi KidoDepartment of Surgical Pathology, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Makoto EmoriDepartment of Orthopedic Surgery, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Yukinori AkiyamaDepartment of Neurosurgery, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Kohichi TakadaDepartment of Medical Oncology, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Shiro HinotsuDepartment of Biostatistics and Data Management, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Tadashi HasegawaDepartment of Surgical Pathology, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan. hasetada@sapmed.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPredicting the prognosis of patients with solitary fibrous tumor (SFT) is often difficult. The prognostic risk models developed by Demicco et al. are now the standard for evaluating the risk of SFT metastasis in the current World Health Organization classification of soft tissue and bone tumors.

methodsIn this study, we examined the prognostic usefulness of a modified version of the Demicco risk models that replaces the mitotic count with the Ki-67 labeling index. We compared the three-variable and four-variable Demicco risk models with our modified risk models using Kaplan-Meier curves based on data for 43 patients with SFT.

resultsWe found a significant difference in metastasis-free survival when patients were classified into low-risk and intermediate/high-risk groups using the three-variable (P = 0.022) and four-variable (P = 0.046) Demicco models. There was also a significant difference in metastasis-free survival between the low-risk and intermediate/high-risk groups when the modified three-variable (P = 0.006) and four-variable (P = 0.022) models were used.

conclusionModified risk models that include the Ki-67 labeling index are effective for prediction of the prognosis in patients with SFT.

Indexed as

Solitary Fibrous TumorsHumansKi-67 AntigenPrognosisKi-67 AntigenKi-67 labeling indexRisk modelSolitary fibrous tumorSTAT6

Identifiers

PMID35105348
PMCPMC8805435

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.