Observational studyHeart & lung : the journal of critical care
Clinical and laboratory predictors at ICU admission affecting course of illness and mortality rates in a tertiary COVID-19 center.
Observational study in Heart & lung : the journal of critical care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Inflammatory Biomarkers as Mediators of the Effect Between High-Dose Corticosteroid Therapy and Mortality in COVID-19-Related ARDS: A Causal Mediation Analysis.Immunity, inflammation and disease · 2026Article
- Pathogen-pathogen interactions during co-infections.The ISME journal · 2025Review
- An elastic net regression model for predicting the risk of ICU admission and death for hospitalized patients with COVID-19.Scientific reports · 2024Article
- Article
- Host Response in Critically Ill Patients Aged 65 Years or Older: A Prospective Study.Clinical interventions in aging · 2024Article
- In-hospital outcomes in patients with and without epilepsy diagnosed with COVID-19-A cohort study.Epilepsia · 2023Article
- A Transcriptomic Severity Classifier IMX-SEV-3b to Predict Mortality in Intensive Care Unit Patients with COVID-19: A Prospective Observational Pilot Study.Journal of clinical medicine · 2023Article
- Efficacy and Safety of Anticoagulant Therapy in COVID-19-Related Pulmonary Embolism with Different Extension.Biomedicines · 2023Article
- Article
- Distribution of Pathogens and Predictive Values of Biomarkers of Inflammatory Response at ICU Admission on Outcomes of Critically Ill COVID-19 Patients with Bacterial Superinfections-Observations from National COVID-19 Hospital in Croatia.Diagnostics (Basel, Switzerland) · 2022Article
- Explainable time-series deep learning models for the prediction of mortality, prolonged length of stay and 30-day readmission in intensive care patients.Frontiers in medicine · 2022Article
- An outcome study in patients with COVID-19 admitted to ICU: HAS a miss?Heart & lung : the journal of critical careArticle
- Author response to: An outcome study in patients with COVID-19 admitted to ICU: HAS a miss?Heart & lung : the journal of critical careArticle
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16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurvival rates of critically ill COVID-19 patients are affected by various clinical features and laboratory parameters at ICU admission. Some of these predictors are universal but others may be population specific.
objectiveTo determine utility of baseline clinical and laboratory parameters in a multivariate regression model to predict outcomes in critically ill COVID-19 patients in a tertiary hospital in Croatia.
methods692 critically ill COVID-19 patients treated during a 10-month period were included in this retrospective observational trial to assess the risk factors determining mortality rates. Various anthropometric features, comorbidities, laboratory parameters, clinical features and therapeutic interventions were included in the analysis. ICU mortality rates and length of ICU stay were primary endpoints analyzed in this study.
resultsAfter multivariate adjustment, only the SOFA score, PaO
conclusionElevated inflammatory biomarkers and SOFA score at ICU admission were detected as significant predictors of ICU mortality in this cohort, while initiation of invasive mechanical ventilation is the most relevant interventional mortality risk factor in critically ill COVID-19 patients.
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