Evidence map›Paper›PMID 35104697›Full record

ReviewBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2022

Treatment and diagnosis of chemotherapy-induced peripheral neuropathy: An update.

Allison D Desforges, Chance M Hebert, Allyson L Spence, Bailey Reid, Hemangini A Dhaibar, Diana Cruz-Topete, Elyse M Cornett, Alan David Kaye, Ivan Urits, Omar Viswanath

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 119 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. [Electrotherapy and sensory re-education as a treatment for chemotherapy-induced neuropathy].Revista medica del Instituto Mexicano del Seguro Social · 2026
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  9. Self-reported peripheral neuropathic symptoms in long-term adolescent and young adult (AYA) cancer survivors: results of the SURVAYA study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
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  20. Spinal P2XPurinergic signalling · 2026
    Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Allison D DesforgesLSU Health Shreveport, Shreveport, LA, USA. Electronic address: adesfo@lsuhsc.edu.
Chance M HebertLSU Health Shreveport, Shreveport, LA, USA. Electronic address: cheb11@lsuhsc.edu.
Allyson L SpenceDepartment of Pharmaceutical Sciences, Regis University School of Pharmacy, Denver, CO 80221, USA. Electronic address: aspence002@regis.edu.
Bailey ReidRegis University School of Pharmacy, Denver, CO 80221, USA. Electronic address: breid002@regis.edu.
Hemangini A DhaibarDepartment of Molecular and Cellular Physiology, LSU Health Shreveport, 1501 Kings Highway, Shreveport, LA 71103, USA. Electronic address: hemangini.dhaibar@lsuhs.edu.
Diana Cruz-TopeteDepartment of Molecular and Cellular Physiology, LSU Health Shreveport, 1501 Kings Highway, Shreveport, LA 71103, USA. Electronic address: diana.cruz@lsuhs.edu.
Elyse M CornettDepartment of Anesthesiology, LSU Health Shreveport, 1501 Kings Highway, Shreveport, LA 71103, USA. Electronic address: elyse.bradley@lsuhs.edu.
Alan David KayeDepartments of Anesthesiology and Pharmacology, Toxicology, and Neurosciences, LSU Health Shreveport, 1501 Kings Highway, Shreveport, LA 71103, USA. Electronic address: alan.kaye@lsuhs.edu.
Ivan UritsBeth Israel Deaconess Medical Center, Department of Anesthesia, Critical Care, and Pain Medicine, 330 Brookline Ave, Boston, MA 02215, USA. Electronic address: ivanurits@gmail.com.
Omar ViswanathValley Anesthesiology and Pain Consultants - Envision Physician Services, Phoenix, AZ, University of Arizona College of Medicine - Phoenix, Department of Anesthesiology, Phoenix, AZ, Creighton University School of Medicine, Department of Anesthesiology, Omaha, NE, USA. Electronic address: viswanoy@gmail.com.
Louisiana State University Health Sciences Center Shreveport · USRegis University · USBeth Israel Deaconess Medical Center · USUniversity of Arizona · US

Funding

Stress Exacerbates Myocardial Ischemic Injury by Blocking Estrogen's Antidoxidant Protection in the Female HeartP20GM121307 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Gopi K Kolluru · 2018 to 2026
$23.6M
Molecular Mechanisms of Stress Signaling in the Female HeartK01HL144882 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI CRUZ TOPETE, DIANA · 2020 to 2024
$694k
NHLBI NIH HHS K01 HL144882NIGMS NIH HHS P20 GM121307
6 · The paper itself

Abstract

When peripheral neuropathy occurs due to chemotherapy treatment, it is referred to as chemotherapy-induced peripheral neuropathy (CIPN). Typically, symptoms are sensory rather than motor and include reduced feeling and heightened sensitivity to pressure, pain, temperature, and touch. The pathophysiology of CIPN is very complex, and it involves multiple mechanisms leading to its development which will be described specifically for each chemotherapeutic class. There are currently no approved or effective agents for CIPN prevention, and Duloxetine is the only medication that is an effective treatment against CIPN. There is an unavoidable necessity to develop preventative and treatment approaches for CIPN due to its detrimental impact on patients' lives. The purpose of this review is to examine CIPN, innovative pharmacological and nonpharmacological therapy and preventive strategies for this illness, and future perspectives for this condition and its therapies.

Indexed as

AnalgesicsAntineoplastic AgentsAntioxidantsComplementary TherapiesHumansNeuroprotective AgentsPatient AcuityPeripheral Nervous System DiseasesRisk FactorsSerotonin and Noradrenaline Reuptake InhibitorsVoltage-Gated Sodium Channel BlockersAnalgesicsAntineoplastic AgentsAntioxidantsNeuroprotective AgentsSerotonin and Noradrenaline Reuptake InhibitorsVoltage-Gated Sodium Channel BlockersChemotherapy-induced peripheral neuropathyIon channel-targeted therapiesNeuropathyPainPain management

Identifiers

PMID35104697
PMCPMC11118018
OpenAlexW4210653950

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.