ArticleExperimental gerontology2022
Factor analysis to determine relative contributions of strength, physical performance, body composition and muscle mass to disability and mobility disability outcomes in older men.
Article in Experimental gerontology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- The association between muscle mass and change in physical functioning in older adults: a systematic review and meta-analysis of prospective studies.European geriatric medicine · 2025Pooled it
- Does Zoledronic Acid Improve Appendicular Lean Mass in Older Women with Osteoporosis? A Sub-Analysis of a Randomized Clinical Trial.The Journal of frailty & aging · 2022Trial
- Sarcopenia in Ageing and Chronic Illness: Trial Endpoints and Regulatory Issues.Journal of cachexia, sarcopenia and muscle · 2025Article
- Muscle Quality and Physical Function in Men With and Without HIV.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Estimating Muscle Mass Using D3-Creatine Dilution: A Narrative Review of Clinical Implications and Comparison With Other Methods.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Review
- DCalcified tissue international · 2024Review
- Predicting Slow Walking Speed From a Pooled Cohort Analysis: Sarcopenia Definitions, Agreement, and Prevalence in Australia and New Zealand.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Synergistic Strategies to Accelerate the Development of Function-Promoting Therapies: Lessons From Operation Warp Speed and Oncology Drug Development.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Effects of Exercise Training on Muscle Quality in Older Individuals: A Systematic Scoping Review with Meta-Analyses.Sports medicine - open · 2023Article
- Sarcopenia ≠ low muscle mass.European geriatric medicine · 2023Article
- DJournal of cachexia, sarcopenia and muscle · 2022Review
- Walking Speed and Muscle Mass Estimated by the DJournal of the American Medical Directors Association · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 8 institutions in 2 countries.
Funding
Abstract
backgroundIt is not known how measures of body composition, strength and physical performance are interrelated or how empirical groupings of these measures relate to disability and mobility disability.
methodsMuscle mass was assessed by D
resultsFactor analysis reduced 10 variables into four factors: Factor 1, body composition, including ALM, body fat percentage, weight and muscle mass; Factor 2, body size and lean mass, including height, weight and ALM; Factor 3, muscle mass, strength and performance, including walk speed, chair stands, grip strength, and muscle mass; and Factor 4, lean mass and weight, including ALM and weight. Only Factor 3 was significantly associated (p-value < .001) with prevalent disability (RR per standard deviation increment in factor score (reflecting higher muscle mass, strength and physical performance) 0.44, 0.35-0.56) and mobility disability (RR 0.22, 0.17 0.28), and incident mobility disability (RR 0.37, 0.27-0.50).
conclusionD
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.