ArticleAngewandte Chemie (International ed. in English)2022
A TMEDA-Iron Adduct Reaction Manifold in Iron-Catalyzed C(sp
Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Iron-mediated C(spTetrahedron · 2025Article
- Iron/phosphine-catalyzed reductive cross-coupling to construct quaternary carbon centers.Nature communications · 2025Article
- Effective Alkyl-Alkyl Cross-Coupling with an Iron-Xantphos Catalyst: Mechanistic and Structural Insights.Angewandte Chemie (International ed. in English) · 2025Article
- Iron-catalysed direct coupling of organosodium compounds.Nature synthesis · 2025Article
- Sequential Iron-Catalyzed C(spMolecules (Basel, Switzerland) · 2022Article
- Up-Scale Synthesis ofACS omega · 2022Article
- General and Practical Route to Diverse 1-(Difluoro)alkyl-3-aryl Bicyclo[1.1.1]pentanes Enabled by an Fe-Catalyzed Multicomponent Radical Cross-Coupling Reaction.ACS catalysis · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Herein, we expand the current molecular-level understanding of one of the most important and effective additives in iron-catalyzed cross-coupling reactions, N,N,N',N'-tetramethylethylenediamine (TMEDA). Focusing on relevant phenyl and ethyl Grignard reagents and slow nucleophile addition protocols commonly used in effective catalytic systems, TMEDA-iron(II)-aryl intermediates are identified via in situ spectroscopy, X-ray crystallography, and detailed reaction studies to be a part of an iron(II)/(III)/(I) reaction cycle where radical recombination with FePhBr(TMEDA) (2
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