Evidence map›Paper›PMID 35104300›Full record

ArticlePloS one2022

High atherogenic risk concomitant with elevated HbA1c among persons with type 2 diabetes mellitus in North Ethiopia.

Hagos Amare Gebreyesus, Girmatsion Fisseha Abreha, Sintayehu Degu Besherae, Merhawit Atsbha Abera, Abraha Hailu Weldegerima, Aregawi Haileslassie Gidey, Afework Mulugeta Bezabih, Tefera Belachew Lemma, Tsinuel Girma Nigatu

Erratum issuedOpen access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hagos Amare GebreyesusDepartment of Nutrition & Dietetics, Jimma University, Jimma, Ethiopia.ORCID 0000-0001-6950-6163
Girmatsion Fisseha AbrehaCollege of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Sintayehu Degu BesheraeCollege of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Merhawit Atsbha AberaCollege of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Abraha Hailu WeldegerimaCollege of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Aregawi Haileslassie GideyCollege of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Afework Mulugeta BezabihCollege of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Tefera Belachew LemmaDepartment of Nutrition & Dietetics, Jimma University, Jimma, Ethiopia.
Tsinuel Girma NigatuDepartment of pediatrics and child health, Jimma University, Jimma, Ethiopia.
Mekelle University · ETJimma University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 2 diabetes mellitus (T2DM) is a chronic disease associated with worse clinical presentation. However, the current investigation practices in Ethiopia have limitations to demonstrate the scope of the clinical burden. Hence, this study was aimed at assessing the glycemic status and coronary heart disease (CHD) risk of persons with T2DM using HbA1c and atherogenic index of plasma (AIP).

methodThis institution-based cross-sectional study was conducted among 421 adults with T2DM from September to November 2019. Demographic, socioeconomic, and lifestyle data were collected through a face-to-face interview. Clinical information was retrieved from medical records whereas anthropometric and biochemical measurements were performed using the WHO protocols. Glycemic status was determined using HbA1c and CHD risk assessed using an atherogenic index of plasma (AIP). Gaussian variables were expressed using mean and standard deviation (SD), Log-normal variables using geometric mean and 95% CI and non- Gaussian variables using median and interquartile ranges. Categorical variables were summarized using absolute frequencies and percentages. Multivariable logistic regression was used to identify factors associated with glycemic control with a statistical significance set at 5%.

resultA total of 195 male and 226 female subjects were involved in this study. The results demonstrated that 77% (324) had HbA1c value ≥7% and 87.2% (367) had high atherogenic risk for CHD. Besides, 57% and 67.9% of persons with T2DM had metabolic syndrome according to International Diabetes Federation (IDF) and the National Cholesterol Education Program-Adult treatment panel III (NCEP-ATP III) criteria, respectively. About 36.8% had one or more comorbidities. Having healthy eating behavior [AOR 1.95; CI 1.11-3.43] and taking metformin [AOR 4.88; CI 1.91-12.44] were associated with better glycemic outcomes.

conclusionHigh AIP level concomitant with poor glycemic control indicates increased risk for coronary heart disease among persons with T2DM in Northern Ethiopia.

Indexed as

AdultAgedComorbidityCoronary DiseaseCross-Sectional StudiesDiabetes Mellitus, Type 2EthiopiaFemaleGlycated HemoglobinHumansInterviews as TopicLife StyleMaleMetforminMiddle AgedOdds RatioGlycated HemoglobinMetformin

Identifiers

PMID35104300
PMCPMC8806058
OpenAlexW4210775742

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.