Evidence map›Paper›PMID 35104001›Full record

Trial reportFASEB journal : official publication of the Federation of American Societies for Experimental Biology2022

Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis.

Jamie D Kraft, Robert Blomgran, Ida Bergström, Matúš Soták, Madison Clark, Alankrita Rani, Meenu Rohini Rajan, Jesmond Dalli, Sofia Nyström, Marianne Quiding-Järbrink and 3 more

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Trial
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Impacts of Oxylipins on ischemic stroke: from pathophysiology to clinical phenotypes.Metabolomics : Official journal of the Metabolomic Society · 2025
    Review
  9. Review
  10. Inflammation and resolution in obesity.Nature reviews. Endocrinology · 2025 · on this map
    Review
  11. Review
  12. Attenuation of adipose tissue inflammation by pro-resolving lipid mediators.Current opinion in endocrine and metabolic research · 2024
    Review
  13. Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Jamie D KraftDepartment of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Robert BlomgranDivision of Inflammation and Infection, Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden.ORCID https://orcid.org/0000-0002-2767-8175
Ida BergströmDepartment of Clinical Immunology and Transfusion Medicine, Linköping University, Linköping, Sweden.
Matúš SotákDepartment of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-9984-9340
Madison ClarkDepartment of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Alankrita RaniDepartment of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Meenu Rohini RajanDepartment of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jesmond DalliWilliam Harvey Research Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0001-6328-3640
Sofia NyströmDepartment of Clinical Immunology and Transfusion Medicine, Linköping University, Linköping, Sweden.
Marianne Quiding-JärbrinkDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jonathan BrombergDepartment of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Per SkoogDepartment of Vascular Surgery and Institute of Medicine, Sahlgrenska University Hospital and Academy, Gothenburg, Sweden.
Emma BörgesonDepartment of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-2290-9472
Sahlgrenska University Hospital · SELinköping University · SEUniversity of Gothenburg · SEQueen Mary University of London · GBUniversity of Maryland, Baltimore · US

Funding

Lymph Node Structure and Function in Tolerance: Role of LamininsR01AI114496 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BROMBERG, JONATHAN S · 2015 to 2024
$4.2M
Regulatory T Cells and Lymphatic Endothelial Cells: Regulatory Interactions for Migration and SuppressionR37AI062765 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Jonathan S Bromberg · 2021 to 2026
$2.9M
NIAID NIH HHS R01 AI114496NIAID NIH HHS R37 AI062765
6 · The paper itself

Abstract

Dysregulated chronic inflammation plays a crucial role in the pathophysiology of atherosclerosis and may be a result of impaired resolution. Thus, restoring levels of specialized pro-resolving mediators (SPMs) to promote the resolution of inflammation has been proposed as a therapeutic strategy for patients with atherosclerosis, in addition to standard clinical care. Herein, we evaluated the effects of the SPM lipids, lipoxin A

Indexed as

AgedAtherosclerosisFemaleHumansInflammationIntegrinsLipoxinsMaleMiddle AgedNeutrophilsRespiratory BurstIntegrinsLipoxinsatherosclerosiscardiovascular diseaseCD11b/CD18 integrinlipoxinslymphatics transmigrationneutrophilsreactive oxygen speciesresolution of inflammationspecialized pro-resolving mediators

Identifiers

PMID35104001
PMCPMC9305188
OpenAlexW4210767557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.