Evidence map›Paper›PMID 35103990›Full record

ArticlePhotochemistry and photobiology2022

Photodynamic Therapy-Induced Cyclooxygenase 2 Expression in Tumor-Draining Lymph Nodes Regulates B-Cell Expression of Interleukin 17 and Neutrophil Infiltration.

Riddhi Falk-Mahapatra, Sandra O Gollnick

Open access · greenAbstract read
In one paragraph

Article in Photochemistry and photobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Riddhi Falk-MahapatraDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Sandra O GollnickDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID 0000-0001-6493-9306
Roswell Park Comprehensive Cancer Center · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
StatisticsP01CA055791 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI PANDEY, RAVINDRA K. · 1992 to 2019
$36.0M
Photodynamic Therapy (PDT) Mechanisms: Tumor ImmunityR01CA098156 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI GOLLNICK, SANDRA O. · 2003 to 2013
$3.6M
MULTIDISCIPLINARY APPROACHES TUMOR IMMUNOLOGYT32CA085183 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Scott I. Abrams · 2001 to 2026
$3.1M
NCI NIH HHS P01 CA055791NCI NIH HHS P30 CA016056NCI NIH HHS R01 CA098156NCI NIH HHS T32 CA085183
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is an effective anticancer modality approved by the U.S. Food and Drug Administration (FDA). Antitumor immunity can be augmented during PDT by inducing sterile inflammation in an acute manner, and this process is characterized by interleukin 17 (IL-17)-mediated neutrophil infiltration to tumor-draining lymph nodes (TDLNs). However, the inflammatory factors that influence IL-17 expression in TDLNs are poorly understood. Prior studies have linked the cyclooxygenase 2 (COX2)-driven prostaglandin E

Indexed as

Interleukin-17NeoplasmsPhotochemotherapyCyclooxygenase 2Cyclooxygenase 2 InhibitorsDinoprostoneHumansLymph NodesNeutrophil InfiltrationNuclear Receptor Subfamily 1, Group F, Member 3Triazenes1-phenyl-3,3-dimethyltriazeneCyclooxygenase 2Cyclooxygenase 2 InhibitorsDinoprostoneInterleukin-17Nuclear Receptor Subfamily 1, Group F, Member 3PTGS2 protein, humanTriazenes

Identifiers

PMID35103990
PMCPMC9484206
OpenAlexW4210388330

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.