ArticleJournal of clinical laboratory analysis2022
Predictive value of NLR and PLR in missed miscarriage.
Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- The predictive value of neutrophil to lymphocyte ratio for abortion: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- The Predictive Significance of Platelet-to-Lymphocyte Ratio for Miscarriage: A Systematic Review and Meta-Analysis.Immunity, inflammation and disease · 2025Pooled it
- Diagnostic value of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio to predict recurrent pregnancy loss and abortion; a systematic review and meta-analysis.Immunity, inflammation and disease · 2024Pooled it
- Comparison of first trimester complete blood count parameters in missed abortion and healthy pregnant women: a retrospective case-control study.BMC pregnancy and childbirth · 2026Article
- Clinical Role of Hematologic Inflammatory Markers in the Diagnosis of Missed Abortion.Saudi medical journal · 2026Article
- Evaluation of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio as Biomarkers in Missed Abortions.Saudi medical journal · 2026Article
- Aortic Elastic Properties and Albumin-Based Inflammatory Indices in Dyspneic Third-Trimester Pregnant Women: A Prospective Observational Study.Biomedicines · 2026Article
- Comparison of serum ınflammatory parameters between spontaneous abortion and threatened abortion.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Predictive Potential of Red Blood Cell Distribution Width and Platelet Ratio (RDW/PLT) in Early Pregnancy Loss.International journal of women's health · 2026Article
- Predicting the risk of threatened abortion using machine learning methods: a comparative study.BMC pregnancy and childbirth · 2025Article
- Inflammatory markers in systemic immune-inflammatory index and inflammatory response index to predict early pregnancy loss.Saudi medical journal · 2024Article
- Systemic Inflammation Response Index and Systemic Immune-inflammation Index for Prediction of Pregnancy Loss: a Case-control Study.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Predicting Potentially Fatal COVID-19 Disease in Pregnant Patients Using the Neutrophil-to-Lymphocyte Ratio (NLR).Journal of clinical medicine · 2023Article
- Prediction of Rupture by Complete Blood Count in Tubal Ectopic Pregnancies Treated with a Single-Dose Methotrexate Protocol.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023Article
- Platelet to lymphocyte and neutrophil to lymphocyte ratio in the first trimester of pregnancy, are they useful for predicting spontaneous miscarriage? A case-control study.International journal of reproductive biomedicine · 2023Article
- Predictive value of NLR and PLR in missed miscarriage.Journal of clinical laboratory analysis · 2022Article
- Exploring the predictive value of complete blood count inflammatory parameters in early pregnancy for missed abortion.Science progressArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe aim of the study was to investigate the predictive value of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in missed miscarriage.
methodsIn this retrospective cohort study, a total of 400 women (involving 200 with missed early miscarriage and 200 with normal pregnancy but terminate by artificial abortion) were included. General clinical data and complete blood count (CBC) such as white blood cells (WBC), red blood cells (RBC), platelet (PLT), red blood cell distribution width-standard deviation (RDW-SD), platelet distribution width (PDW), mean platelet volume (MPV), neutrophil count, and lymphocyte count were collected, and the NLR and PLR were calculated for both groups. Receiver operating characteristic curve (ROC) was used to calculate the predictive value.
resultsThere was no significant difference in the WBC, RBC, PLT, RDW-SD, PDW, neutrophil, lymphocyte, NLR, and PLR between the two groups (p > 0.05).But MPV was lower in the missed early miscarriage group than in the control group (p < 0.05), and the area under the working curve (AUC) of ROC was 0.58, specificity and sensitivity was 69% and 47%, respectively.
conclusionNLR and PLR were not the suitable indictor for missed miscarriage, but MPV should be a concern in the first trimester.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.