Evidence map›Paper›PMID 35103970›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Genome-Wide Mapping and Microscopy Visualization of Protein-DNA Interactions by pA-DamID.

Tom van Schaik, Stefano G Manzo, Bas van Steensel

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tom van SchaikOncode Institute and Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Stefano G ManzoOncode Institute and Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Bas van SteenselOncode Institute and Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands. b.v.steensel@nki.nl.
Oncode Institute · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several methods have been developed to map protein-DNA interactions genome-wide in the last decades. Protein A-DamID (pA-DamID) is a recent addition to this list with distinct advantages. pA-DamID relies on antibody-based targeting of the bacterial Dam enzyme, resulting in adenine methylation of DNA in contact with the protein of interest. This

Indexed as

MicroscopyStaphylococcal Protein AChromatinDNADNA MethylationChromatinDNAStaphylococcal Protein AChromatinFluorescence microscopyGenome-wide mappingHigh-throughput sequencingm6A-tracerNuclear laminaProtein A-DamID (pA-DamID)Protein–DNA interactions

Identifiers

PMID35103970
OpenAlexW4210243699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.