Evidence map›Paper›PMID 35103957›Full record

ReviewCurrent environmental health reports2022

The Effects of Environmental Contaminant Exposure on Reproductive Aging and the Menopause Transition.

Alison M Neff, Mary J Laws, Genoa R Warner, Jodi A Flaws

Open access · greenAbstract readReview
In one paragraph

Review in Current environmental health reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
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  6. Review
  7. Article
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  10. Review
  11. PFAS and their association with the increased risk of cardiovascular disease in postmenopausal women.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Article
  12. Article
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  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alison M NeffDepartment of Comparative Biosciences, University of Illinois at Urbana-Champaign, 2001 South Lincoln Avenue, 3223 Vet Med Basic Sciences Bldg, Urbana, IL, 61802, USA.
Mary J LawsDepartment of Comparative Biosciences, University of Illinois at Urbana-Champaign, 2001 South Lincoln Avenue, 3223 Vet Med Basic Sciences Bldg, Urbana, IL, 61802, USA.
Genoa R WarnerDepartment of Comparative Biosciences, University of Illinois at Urbana-Champaign, 2001 South Lincoln Avenue, 3223 Vet Med Basic Sciences Bldg, Urbana, IL, 61802, USA.
Jodi A FlawsDepartment of Comparative Biosciences, University of Illinois at Urbana-Champaign, 2001 South Lincoln Avenue, 3223 Vet Med Basic Sciences Bldg, Urbana, IL, 61802, USA. jflaws@illinois.edu.
University of Illinois Urbana-Champaign · US

Funding

Research Training Program in Toxicology and Environmental HealthT32ES007326 · NIEHS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI Jodi A. Flaws · 2000 to 2026
$8.7M
Phthalates and Ovarian ToxicityR01ES028661 · NIEHS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI FLAWS, JODI A. · 2018 to 2022
$1.8M
Mechanisms of Phthalate Toxicity in the OvaryK99ES031150 · NIEHS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI WARNER, GENOA R · 2020 to 2021
$194k
NIEHS NIH HHS K99 ES031150NIEHS NIH HHS R01 ES028661NIEHS NIH HHS T32 ES007326
6 · The paper itself

Abstract

purpose of reviewMenopause marks the end of a woman's reproductive lifetime. On average, natural menopause occurs at 51 years of age. However, some women report an earlier age of menopause than the national average. This can be problematic for women who delay starting a family. Moreover, early onset of menopause is associated with increased risk of cardiovascular disease, depression, osteoporosis, and premature death. This review investigates associations between exposure to endocrine-disrupting chemicals (EDCs) and earlier onset of menopause. RECENT

findingsRecent data suggest exposure to certain EDCs may accelerate reproductive aging and contribute to earlier onset of menopause. Human and rodent-based studies identify positive associations between exposure to certain EDCs/environmental contaminants and reproductive aging, earlier onset of menopause, and occurrence of vasomotor symptoms. These findings increase our understanding of the detrimental effects of EDCs on female reproduction and will help lead to the development of strategies for the treatment/prevention of EDC-induced reproductive aging.

Indexed as

Endocrine DisruptorsReproductionAgingEnvironmental ExposureFemaleHumansMenopauseEndocrine DisruptorsEndocrine-disrupting chemicalsMenopauseOvary

Identifiers

PMID35103957
PMCPMC8988816
OpenAlexW4210498969

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.