Evidence map›Paper›PMID 35103908›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2022

Expert consensus to optimize the treatment of elderly patients with luminal metastatic breast cancer.

M D Torregrosa-Maicas, S Del Barco-Berrón, A Cotes-Sanchís, L Lema-Roso, S Servitja-Tormo, R Gironés-Sarrió

Open access · hybridAbstract readReviewConsensus Statement
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Strategies to enhance management of HER2-positive breast cancer in the elderly: an expert consensus perspective.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Elderly patients with hormone receptor-positive HER2-negative metastatic breast cancer treated with CDK4/6 inhibitors in a multicentre cohort.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Observational
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

M D Torregrosa-MaicasOncogeriatric Section, Sociedad Española de Oncología Médica (SEOM), Doctor Peset University Hospital, Avda. de Gaspar Aguilar, 90, 46017, Valencia, Spain. marilotorre@gmail.com.ORCID http://orcid.org/0000-0002-1285-1131
S Del Barco-BerrónOncogeriatric Section, Sociedad Española de Oncología Médica (SEOM), Doctor Josep Trueta University Hospital, Insituto Catalán de Oncología (ICO), Girona, Spain.
A Cotes-SanchísOncogeriatric Section, Sociedad Española de Oncología Médica (SEOM), Elda-Virgen de La Salud University Hospital, Alicante, Spain.
L Lema-RosoGrupo Cooperativo de Investigación Clínica en Cáncer de Mama (SOLTI), Doce de Octubre University Hospital, Madrid, Spain.
S Servitja-TormoGrupo Español de Investigación en Cáncer de Mama (GEICAM), Hospital del Mar-Parc de Salut Mar, Barcelona, Spain.
R Gironés-SarrióOncogeriatric Section, Sociedad Española de Oncología Médica (SEOM), La Fe University Hospital, Valencia, Spain.
Sociedad Española de Oncología Médica · ESHospital Universitario Doctor Peset · ESInstitut Català d'Oncologia · ESParc de Salut · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most patients diagnosed with luminal metastatic breast cancer (MBC) who are seen in oncology consultations are elderly. MBC in elderly patients is characterized by a higher percentage of hormone receptor (HR) expression and a lower expression of human epidermal growth factor receptor 2 (HER2). The decision regarding which treatment to administer to these patients is complex due to the lack of solid evidence to support the decision-making process. The objective of this paper is to review the scientific evidence on the treatment of elderly patients with luminal MBC. For this purpose, the Oncogeriatrics Section of the Spanish Society of Medical Oncology (SEOM), the Spanish Breast Cancer Research Group (GEICAM) and the SOLTI Group appointed a group of experts who have worked together to establish consensus recommendations to optimize the treatment of this population. It was concluded that the chronological age of the patient alone should not guide therapeutic decisions and that a Comprehensive Geriatric Assessment (CGA) should be performed whenever possible before establishing treatment. Treatment selection for the elderly population should consider the patient's baseline status, the expected benefit and toxicity of each treatment, and the impact of treatment toxicity on the patient's quality of life and functionality.

Indexed as

Breast NeoplasmsAgedAge FactorsBreastConsensusErb-b2 Receptor Tyrosine KinasesFemaleGeriatric AssessmentHumansQuality of LifeErb-b2 Receptor Tyrosine KinasesCyclin inhibitorsGeriatricsHormone therapymTOR inhibitorsPARP inhibitorsPI3K inhibitors

Identifiers

PMID35103908
PMCPMC9107453
OpenAlexW4210395544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.