Evidence map›Paper›PMID 35103880›Full record

ArticleJournal of neurovirology2022

CSF markers of AD-related pathology relate specifically to memory impairment in older people with HIV: a pilot study.

Judith D Lobo, David J Moore, Mark W Bondi, Virawudh Soontornniyomkij, Benchawanna Soontornniyomkij, Ben Gouaux, Cristian L Achim, Ronald J Ellis, Erin E Sundermann

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurovirology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Judith D LoboDepartment of Psychiatry, University of California, 220 Dickinson St, #B, San Diego, CA, 92103, USA. jlobo@health.ucsd.edu.ORCID 0000-0002-2223-1518
David J MooreDepartment of Psychiatry, University of California, 220 Dickinson St, #B, San Diego, CA, 92103, USA.
Mark W BondiDepartment of Psychiatry, University of California, 220 Dickinson St, #B, San Diego, CA, 92103, USA.
Virawudh SoontornniyomkijDepartment of Psychiatry, University of California, 220 Dickinson St, #B, San Diego, CA, 92103, USA.
Benchawanna SoontornniyomkijDepartment of Psychiatry, University of California, 220 Dickinson St, #B, San Diego, CA, 92103, USA.
Ben GouauxDepartment of Psychiatry, University of California, 220 Dickinson St, #B, San Diego, CA, 92103, USA.
Cristian L AchimDepartment of Psychiatry, University of California, 220 Dickinson St, #B, San Diego, CA, 92103, USA.
Ronald J EllisDepartment of Neurosciences, University of California, San Diego, USA.
Erin E SundermannDepartment of Psychiatry, University of California, 220 Dickinson St, #B, San Diego, CA, 92103, USA.
University of California San Diego · US

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
California NeuroAIDS Tissue NetworkU24MH100928 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ACHIM, CRISTIAN L, MOORE, DAVID J · 2013 to 2023
$13.9M
Interdisciplinary Research Fellowship in NeuroAIDSR25MH081482 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MARIANA CHERNER · 2007 to 2026
$5.2M
Training in Research on Addictions in Interdisciplinary NeuroAIDS (TRAIN)T32DA031098 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello, DAVID J MOORE · 2011 to 2026
$4.6M
Re-visiting Methods for MCI Diagnosis to Improve Biomarker and Trial FindingsR01AG049810 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BONDI, MARK W, EDLAND, STEVEN DYAL · 2016 to 2020
$3.7M
Disentangling Alzheimer's disease and HIV-Associated Neurocognitive Disorder: Identifying unique neuropsychological profiles with distinct biomarker and neuropathological signaturesRF1AG061070 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BONDI, MARK W, MOORE, DAVID J · 2018 to 2024
$3.1M
Sustained Training in Aging and HIV Research (STAHR)R25MH108389 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Scott L Letendre, DAVID J MOORE · 2016 to 2026
$1.9M
CNS HIV ANTI-RETROVIRAL THERAPY EFFECTS RESEARCH /CHARTER/ -278022005-278022005N01MH022005 · NIMH · UNIVERSITY OF CA -SAN DIEGO · PI GRANT, IGOR · 2003 to 2006
–
NIA NIH HHS R01 AG049810NIA NIH HHS RF1 AG061070NIDA NIH HHS T32 DA031098NIMH NIH HHS HHSN271201000030CNIMH NIH HHS HHSN271201000036CNIMH NIH HHS N01 MH022005NIMH NIH HHS P30 MH062512NIMH NIH HHS R25 MH081482NIMH NIH HHS R25 MH108389NIMH NIH HHS U24 MH100928
6 · The paper itself

Abstract

Given the co-occurrence of memory impairment in HIV-associated neurocognitive disorders (HAND) and amnestic mild cognitive impairment/Alzheimer's disease (aMCI/AD), biomarkers are needed that can disentangle these conditions among people with HIV (PWH). We assessed whether cerebrospinal fluid (CSF) markers of AD could help in this effort by determining their relationship to learning and memory deficits versus cognitive deficits more characteristic of HAND than aMCI/AD (processing speed and complex visual/motor coordination) among 31 older PWH. CSF amyloid-β

Indexed as

Alzheimer DiseaseCognitive DysfunctionHIV InfectionsAgedAmyloid beta-PeptidesBiomarkersHumansMemory DisordersNeuropsychological TestsPeptide FragmentsPilot Projectstau ProteinsAmyloid beta-PeptidesBiomarkersPeptide Fragmentstau ProteinsAlzheimer’s diseaseAmyloidBiomarkersHIV-associated neurocognitive disordersMild cognitive impairmentTau

Identifiers

PMID35103880
PMCPMC9081235
OpenAlexW4210432486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.