ArticleEuropean journal of applied physiology2022
Changes in cardiac function following a speed ascent to the top of Europe at 4808 m.
Article in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Right ventricular strain impairment due to hypoxia in patients with COPD: a post hoc analysis of two randomised controlled trials.Open heart · 2025Trial
- Left ventricular hypertrophy and myocardial work in amateur marathon runners.Frontiers in cardiovascular medicine · 2025Article
- Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia.Scientific reports · 2024Article
- Editorial on the Research Topic the 2nd Edition of Mountain Sports Activities: Injuries and Prevention.International journal of environmental research and public health · 2022Article
- Changes in cardiac function following a speed ascent to the top of Europe at 4808 m.European journal of applied physiology · 2022Article
- Exercise-induced myocardial edema in master triathletes: Insights from cardiovascular magnetic resonance imaging.Frontiers in cardiovascular medicine · 2022Article
- Cardiac Adaptation to Prolonged High Altitude Migration Assessed by Speckle Tracking Echocardiography.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBoth prolonged exercise and acute high-altitude exposure are known to induce cardiac changes. We sought to describe the cardiac responses to speed climbing at high-altitude, including left ventricular (LV) performance assessment using the myocardial work index (MWI), a new index derived from 2D speckle tracking echocardiography (STE).
methodsEleven elite alpinists (9 males, age: 26 ± 4 years) were evaluated before and immediately after a speed ascent of the Mont-Blanc (4808 m) by echocardiography using conventional measurements as well as STE and MWI computation with derivate parameters as global work efficiency (GWE) or global wasted work (GWW).
resultsAthletes performed a long-duration (8 h 58 min ± 60 min) and intense (78 ± 4% of maximal heart rate) ascent under gradual hypoxic conditions (minimal SpO
conclusionsProlonged high-altitude speed climbing in elite climbers is associated with RV and LV function changes with a major interaction alteration. MWI, assessing the myocardial performance, could be a new tool for evaluating LV exercise-induced cardiac fatigue.
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