Evidence map›Paper›PMID 35103798›Full record

ArticleTranslational vision science & technology2022

Hydrodynamic Interaction Between Tear Film and Air Puff From Noncontact Tonometry.

Atieh Yousefi, Yanhui Ma, Cynthia J Roberts, Sayoko E Moroi, Matthew A Reilly

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Atieh YousefiDepartment of Ophthalmology & Visual Sciences, The Ohio State University College of Medicine, Columbus, OH, USA.
Yanhui MaDepartment of Ophthalmology & Visual Sciences, The Ohio State University College of Medicine, Columbus, OH, USA.
Cynthia J RobertsDepartment of Ophthalmology & Visual Sciences, The Ohio State University College of Medicine, Columbus, OH, USA.
Sayoko E MoroiDepartment of Ophthalmology & Visual Sciences, The Ohio State University College of Medicine, Columbus, OH, USA.
Matthew A ReillyDepartment of Ophthalmology & Visual Sciences, The Ohio State University College of Medicine, Columbus, OH, USA.
The Ohio State University · US

Funding

Corneal Biomechanics in Ocular DiseaseR01EY027399 · NEI · OHIO STATE UNIVERSITY · PI CYNTHIA J ROBERTS · 2017 to 2026
$3.8M
NEI NIH HHS R01 EY027399
6 · The paper itself

Abstract

purposeThe purpose of this study was to investigate the mechanism of potential droplet formation in response to air puff deformation with two noncontact tonometers (NCTs).

methodsTwenty healthy volunteers were examined using two NCTs, Ocular Response Analyzer and Corvis ST, and two contact tonometers, iCare and Tono-Pen. High-speed videos of the tear film response were captured with at spatial resolution of 20 microns/pixel at 2400 fps. Droplet size, droplet velocity, distance between air puff impact location, and the tear meniscus-lid margin were characterized.

resultsOne subject was excluded due to technical issues. Droplets were detected only in tests with instilled eye drop. Videos showed the tear film rolls away from the apex while remaining adherent to the ocular surface due to the tendency of the fluid to remain attached to a solid surface explained by the Coanda effect. Twelve out of 38 videos with an eye drop administration showed droplet formation. Only one resulted in droplets with predominantly forward motion, which had the shortest distance between air puff impact location and lower meniscus. This distance on average was 5.9 ± 1.1 mm. The average droplet size was 500 ± 200 µm.

conclusionsResults indicate no droplet formation under typical clinical setting. Hence, standard clinical use of NCT tests is not expected to cause droplets. NCT testing with eye drop administration showed droplet formation at the inferior eyelid boundary, which acts as a barrier and interrupts tear flow. TRANSLATIONAL RELEVANCE: Study of tear film interaction with NCT air puff shows that these tonometers are not expected to cause droplet formation in standard use and that if external drops are required, both eyelids should be held if patients need assistance to maintain open eyes to avoid droplets with predominantly forward motion.

Indexed as

HydrodynamicsLacerationsHumansIntraocular PressureManometryOphthalmic SolutionsTonometry, OcularOphthalmic Solutions

Identifiers

PMID35103798
PMCPMC8819281
OpenAlexW4210379465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.