ArticleInternational journal of fertility & sterility2022
A Comparison of Shear Wave Elastography between Normal Myometrium, Uterine Fibroids, and Adenomyosis: A Cross-Sectional Study.
Article in International journal of fertility & sterility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 16 citations in OpenAlex.
- Model Based on Ultrasound Radiomics and Machine Learning for Differentiating Uterine Fibroids and Adenomyomas.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Article
- Ultrasound Elastography in the Diagnosis and Management of Uterine Pathologies: A Systematic Review.Journal of clinical medicine · 2026Review
- Increased Junctional Zone Stiffness and Serum Small Extracellular Vesicle Proteomic Signatures in Adenomyosis-Associated Infertility: An Exploratory SWE and Proteomic Study.International journal of women's health · 2026Article
- Evaluation of stiffness values of normal uterine myometrium by 3T magnetic resonance elastography.Frontiers in medicine · 2026Article
- The correlation between stiffness and viscoelasticity of the myometrium in adenomyosis: a prospective study.Quantitative imaging in medicine and surgery · 2025Article
- Advances in non-invasive diagnosis of uterine adenomyosis: a narrative review.Gynecology and pelvic medicine · 2025Review
- Decoding uterine (dys)function in fibroids through multimodal assessment of functional determinants: a systematic review and meta-analysis.Human reproduction open · 2025Review
- Non-invasive endometrial assessment: shear wave elastography in diagnosing endometrial hyperplasia.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Ultrasound Elastography in Benign Gynecology: A Scoping Review.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Clinical experience with shear wave elastography (SWE) for assessing healthy uterus in a transabdominal approach.Scientific reports · 2024Article
- Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease†.Biology of reproduction · 2024Review
- Evidence-Based Approach for Secondary Prevention of Uterine Fibroids (The ESCAPE Approach).International journal of molecular sciences · 2023Review
- Prevention of Uterine Fibroids: molecular mechanisms and potential clinical application.Journal of endometriosis and uterine disorders · 2023Article
- In Search of an Imaging Classification of Adenomyosis: A Role for Elastography?Journal of clinical medicine · 2022Review
- Advances in the clinical application of ultrasound elastography in uterine imaging.Insights into imaging · 2022Review
- Transvaginal Ultrasound Combined with Strain-Ratio Elastography for the Concomitant Diagnosis of Uterine Fibroids and Adenomyosis: A Pilot Study.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe differential diagnosis between uterine fibroid and adenomyosis is sometimes difficult; a precise diagnosis is required in women with infertility because of the different choice of treatments. Ultrasound elastography (UE) is a novel technique to evaluate the elasticity or the stiffness of the tissue of interest. The present study aims to compare UE shear wave velocity (SWV) among normal uterine myometrium, uterine fibroid, and adenomyosis, and assess the accuracy of shear wave elastography in the diagnosis of adenomyosis. MATERIALS AND
methodsThis cross-sectional study recruited 25 subjects for each group (control, adenomyosis, and fibroid) from April 2019 to April 2020. Transvaginal UE using an Aplio 500 (Toshiba Medical Systems, Japan) with ultrasound mapping for point of tissue biopsy was performed for all subjects. The diagnosis was confirmed by histology. Masson's trichrome staining for collagen was performed and quantified.
resultsThe mean ± standard deviation (SD) for SWV was 3.44 ± 0.95 m/seconds (control group), 4.63 ± 1.45 m/ seconds (adenomyosis group), and 4.53 ± 1.07 m/seconds (fibroid group). The mean SWV differed when comparing normal myometrium and adenomyosis after adjustments for age and endometrial pathology (P=0.019). The cut-off point of SWV at 3.465 m/seconds could differentiate adenomyosis from the normal uterus with an 80% sensitivity, 80% specificity, and an area under the curve (AUC) of 0.80 (95% confidence interval [CI]: 0.68-0.93) (P<0.001). No significant difference in SWV between the adenomyosis and fibroid groups was detected.
conclusionShear wave elastography could be an alternative tool to distinguish between normal myometrium and adenomyosis; however, it could not differentiate adenomyosis from uterine fibroid or uterine fibroid from normal myometrium.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.