A Possible Trait and Status Marker in Bipolar Disorder: The Electroretinogram-Pattern.

Pilar Sierra, María Fernanda González, Julia Buesa, Joana Catalina Cardozo, José Manuel Matamoros, Ana García-Blanco, Lorenzo Livianos

Abstract read

PubMed Full text at PMC

In one paragraph

Article in Actas espanolas de psiquiatria, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Oculomics: advances and perspectives from traditional Chinese medicine to modern multimodal biomarkers.International journal of ophthalmology · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pilar SierraDepartment of Psychiatry, La Fe University and Polytechnic Hospital, Valencia, Spain Department of Medicine, University of Valencia de Valencia, Valencia, Spain.

María Fernanda GonzálezDepartment of Psychiatry, Infanta Cristina University Hospital, Madrid, Spain.

Julia BuesaDepartment of Psychiatry, La Fe University and Polytechnic Hospital, Valencia, Spain.

Joana Catalina CardozoDepartment of Psychiatry, Infanta Cristina University Hospital, Madrid, Spain.

José Manuel MatamorosDepartment of Psychiatry, La Fe University and Polytechnic Hospital, Valencia, Spain b Department of Medicine, University of Valencia de Valencia, Valencia, Spain.

Ana García-BlancoLa Fe Social Health Research Institute, Valencia, Spain.

Lorenzo LivianosDepartment of Medicine, University of Valencia de Valencia, Valencia, Spain CIBERESP-17, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The similarity between retinal cells and neurons of the central nervous system allows non-invasive methods to study retinal function, such as the Electroretinogram-Pattern (PERG) to be postulated as possible biomarkers, useful and safe in the study of psychiatric pathologies such as Bipolar Disorder (BD). The objective of the present study is to characterize the differences in the results in the PERG of patients with BD and healthy subjects, as well as to evaluate a possible correlation between these results and the affective decompensations of the manic pole in the group of bipolar patients.

Indexed as

Bipolar DisorderBiomarkersHumansBiomarkers

Identifiers

PMID35103296

PMCPMC10803831

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.