ArticleCureus2022
Use of the Sphenopalatine Ganglion Block to Treat Migraine Headaches in the Emergency Department.
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06310200 (Involvement of the Sphenopalatine Ganglion in Cold Induced Headaches), which is not on this map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Involvement of the Sphenopalatine Ganglion in Cold Induced Headaches
Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Article
- Ultrasound-Guided Nerve Block: A Potential Intervention for Drug-Refractory Allergic Rhinitis.Clinical case reports · 2025Article
- The Ganglia of the Head and Neck: Clinical Relevance for the Interventional Pain Physician.Current pain and headache reports · 2025Review
- Literature Review: Pericranial Nerve Blocks for Chronic Migraines.Health psychology research · 2023Article
- Sphenopalatine ganglion (SPG) blocks: Evidence and implementation for acute migraine treatment in the primary care setting.The journal of medicine accessArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Headaches are a common presenting complaint to the emergency department. Amongst the common non-life-threatening headaches, migraine headaches tend to be one of the more severe. Commonly, migraines are treated with the so-called "migraine cocktail." At our facility, this cocktail is usually IV fluids, metoclopramide, diphenhydramine, and ketorolac. The patient is then left in a quiet, dark room for two to three hours, then reassessed for symptom improvement or if more medications are required. Recently we have begun to employ the sphenopalatine ganglion (SPG) block as a rapid, and easy-to-administer alternative to the classic migraine cocktail. The SPG block can often provide sufficient improvement of symptoms within 15 minutes to allow the patient to be discharged. Patients are grateful to have such rapid pain relief, and the ED flow is improved with a door-to-discharge time that can be less than an hour. The following is a series of three recent cases where we have used the SPG block to treat migraines in our ED patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.