Evidence map›Paper›PMID 35102222›Full record

ArticleScientific reports2022

Investigating the human jejunal microbiota.

Heidi Cecilie Villmones, Marius Svanevik, Elling Ulvestad, Tore Stenstad, Inger Lill Anthonisen, Randi Monsen Nygaard, Ruben Dyrhovden, Øyvind Kommedal

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Effects of High-Fat Diet on Intestinal Microbiota in Largemouth Bass (Animals : an open access journal from MDPI · 2026
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  3. Unprecedented Pseudotumor Formation inArthroplasty today · 2026
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  13. Novel potential biomarkers for predicting childhood caries via metagenomic analysis.Frontiers in cellular and infection microbiology · 2025
    Article
  14. Review
  15. Re-framing the importance of Group BInfection and immunity · 2024
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Heidi Cecilie VillmonesDepartment of Microbiology, Vestfold Hospital Trust, Postbox 2168, 3103, Tønsberg, Norway. heivil@siv.no.
Marius SvanevikDepartment of Gastrointestinal Surgery, Vestfold Hospital Trust, 3103, Tønsberg, Norway.
Elling UlvestadDepartment of Clinical Science, University of Bergen, 5021, Bergen, Norway.
Tore StenstadDepartment of Infectious Medicine, Vestfold Hospital Trust, 3103, Tønsberg, Norway.
Inger Lill AnthonisenDepartment of Microbiology, Vestfold Hospital Trust, Postbox 2168, 3103, Tønsberg, Norway.
Randi Monsen NygaardDepartment of Microbiology, Haukeland University Hospital, 5021, Bergen, Norway.
Ruben DyrhovdenDepartment of Microbiology, Haukeland University Hospital, 5021, Bergen, Norway.
Øyvind KommedalDepartment of Clinical Science, University of Bergen, 5021, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Descriptions of the small intestinal microbiota are deficient and conflicting. We aimed to get a reliable description of the jejunal bacterial microbiota by investigating samples from two separate jejunal segments collected from the luminal mucosa during surgery. Sixty patients with morbid obesity selected for elective gastric bypass surgery were included in this survey. Samples collected by rubbing a swab against the mucosa of proximal and mid jejunal segments were characterized both quantitatively and qualitatively using a combination of microbial culture, a universal quantitative PCR and 16S deep sequencing. Within the inherent limitations of partial 16S sequencing, bacteria were assigned to the species level. By microbial culture, 53 patients (88.3%) had an estimated bacterial density of < 1600 cfu/ml in both segments whereof 31 (51.7%) were culture negative in both segments corresponding to a bacterial density below 160 cfu/ml. By quantitative PCR, 46 patients (76.7%) had less than 10

Indexed as

Gastrointestinal MicrobiomeAdultAgedBacteriaDNA, BacterialFemaleGastric BypassHigh-Throughput Nucleotide SequencingHumansIntestinal MucosaJejunumMaleMiddle AgedObesity, MorbidReal-Time Polymerase Chain ReactionRibotypingDNA, Bacterial

Identifiers

PMID35102222
PMCPMC8803847

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.