ArticleProceedings of the National Academy of Sciences of the United States of America2022
Distinguishing the molecular diversity, nutrient content, and energetic potential of exometabolomes produced by macroalgae and reef-building corals.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 84 citations in OpenAlex.
- Enhancing Molecular Change: Iron-Mediated Photochemistry Increases DOM Transformation in Tropical Peatland Canals.Environmental science & technology · 2026Article
- Bacteriophage replication strategies are associated with organic matter energy content on coral reefs.mSystems · 2026Article
- The Distribution of Xenobiotics of Terrigenous Origin in the Nearshore Waters of a Caribbean Island.Environmental science & technology · 2026Article
- Practical guide for marine exo-metabolomic sample preparation.The ISME journal · 2026Review
- Spatiotemporal and hydrodynamic influences on microbial and exometabolite dynamics in coral reef and seagrass ecosystems.The ISME journal · 2026Article
- Impacts of Nearby Algae on Recruitment Success and Early Microbiome Development of the Coral Acropora cytherea.Environmental microbiology · 2026Article
- Article
- Species-specific metabolomic profiles of coral reef coralline algae and their influence on the larval settlement of corals and crown-of-thorns starfish.Scientific reports · 2025Article
- Contact- and Water-Mediated Interactions With an Allelopathic Macroalga Drive Distinct Coral Microbiome and Metabolome.Environmental microbiology · 2025Article
- A control theory framework and in situ experimental platform for informing restoration of coral reefs.Nature ecology & evolution · 2025Review
- Microbial Community Metabolism of Coral Reef Exometabolomes Broadens the Chemodiversity of Labile Dissolved Organic Matter.Environmental microbiology · 2025Article
- Resolving Symbiodiniaceae Diversity Across Coral Microhabitats and Reef Niches.Environmental microbiology · 2025Article
- Oxidation state of bioavailable dissolved organic matter influences bacterioplankton respiration and growth efficiency.Communications biology · 2025Article
- Invasive macroalgae shape chemical and microbial waterscapes on coral reefs.Communications biology · 2025Article
- Statistical analysis of feature-based molecular networking results from non-targeted metabolomics data.Nature protocols · 2025Article
- Submarine groundwater discharge drives both direct and indirect effects on organismal and community metabolism on coral reefs.Proceedings. Biological sciences · 2025Article
- Sponge exhalent metabolites influence coral reef picoplankton dynamics.Scientific reports · 2024Article
- High diversity of crustose coralline algae microbiomes across species and islands, and implications for coral recruits.Environmental microbiome · 2024Article
- Metabolomic profiles of stony coral species from the Dry Tortugas National Park display inter- and intraspecies variation.mSystems · 2024Article
- Coral high molecular weight carbohydrates support opportunistic microbes in bacterioplankton from an algae-dominated reef.mSystems · 2024Article
Corrections and comments
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Authors and funding
15 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolites exuded by primary producers comprise a significant fraction of marine dissolved organic matter, a poorly characterized, heterogenous mixture that dictates microbial metabolism and biogeochemical cycling. We present a foundational untargeted molecular analysis of exudates released by coral reef primary producers using liquid chromatography-tandem mass spectrometry to examine compounds produced by two coral species and three types of algae (macroalgae, turfing microalgae, and crustose coralline algae [CCA]) from Mo'orea, French Polynesia. Of 10,568 distinct ion features recovered from reef and mesocosm waters, 1,667 were exuded by producers; the majority (86%) were organism specific, reflecting a clear divide between coral and algal exometabolomes. These data allowed us to examine two tenets of coral reef ecology at the molecular level. First, stoichiometric analyses show a significantly reduced nominal carbon oxidation state of algal exometabolites than coral exometabolites, illustrating one ecological mechanism by which algal phase shifts engender fundamental changes in the biogeochemistry of reef biomes. Second, coral and algal exometabolomes were differentially enriched in organic macronutrients, revealing a mechanism for reef nutrient-recycling. Coral exometabolomes were enriched in diverse sources of nitrogen and phosphorus, including tyrosine derivatives, oleoyl-taurines, and acyl carnitines. Exometabolites of CCA and turf algae were significantly enriched in nitrogen with distinct signals from polyketide macrolactams and alkaloids, respectively. Macroalgal exometabolomes were dominated by nonnitrogenous compounds, including diverse prenol lipids and steroids. This study provides molecular-level insights into biogeochemical cycling on coral reefs and illustrates how changing benthic cover on reefs influences reef water chemistry with implications for microbial metabolism.
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Registered trials
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