Evidence map›Paper›PMID 35101766›Full record

ArticleJournal of the neurological sciences2022

Head tremor in cervical dystonia: Quantifying severity with computer vision.

Jeanne P Vu, Elizabeth Cisneros, Ha Yeon Lee, Linh Le, Qiyu Chen, Xiaoyan A Guo, Ryin Rouzbehani, Joseph Jankovic, Stewart Factor, Christopher G Goetz and 8 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the neurological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Video-Based Data-Driven Models for Diagnosing Movement Disorders: Review and Future Directions.Movement disorders : official journal of the Movement Disorder Society · 2025
    Review
  6. Review
  7. Article
  8. Hold that pose: capturing cervical dystonia's head deviation severity from video.Annals of clinical and translational neurology · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 1 country.

Jeanne P VuInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Elizabeth CisnerosInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Ha Yeon LeeInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Linh LeInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Qiyu ChenInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Xiaoyan A GuoInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Ryin RouzbehaniInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Joseph JankovicParkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA.
Stewart FactorDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Christopher G GoetzDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
Richard L BarbanoDepartment of Neurology, University of Rochester, Rochester, NY, USA.
Joel S PerlmutterDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Departments of Radiology, Neuroscience, Physical Therapy, and Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA.
Hyder A JinnahDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA; Departments of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Sarah Pirio RichardsonDepartment of Neurology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Neurology Service, New Mexico Veterans Affairs Health Care System, Albuquerque, NM, USA.
Glenn T StebbinsDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
Rodger ElbleDepartment of Neurology, Southern Illinois University School of Medicine, Springfield, IL, USA.
Cynthia L ComellaDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
David A PetersonInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA; Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA. Electronic address: dap@salk.edu.
University of California, San Diego · USRush University Medical Center · USEmory University · USBaylor College of Medicine · USSalk Institute for Biological Studies · USSouthern Illinois University School of Medicine · USUniversity of New Mexico · USUniversity of Rochester · USWashington University in St. Louis · US

Funding

Medicinal Chemistry CoreU19NS110456 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI ROBERT H MACH · 2019 to 2026
$44.1M
INVESTIGATIONS OF DEMENTIA IN PARKINSON DISEASER01NS075321 · NINDS · WASHINGTON UNIVERSITY · PI CAMPBELL, MEGHAN C, PERLMUTTER, JOEL SYNES · 2011 to 2021
$8.2M
Dystonia Coalition- Pilot ProjectU54NS116025 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2019 to 2023
$7.1M
Dystonia CoalitionU54NS065701 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2009 to 2014
$7.0M
Protein Aggregation and Neurotransmitter Deficits in Parkinson DiseaseR01NS097799 · NINDS · WASHINGTON UNIVERSITY · PI PAUL T KOTZBAUER · 2016 to 2026
$5.8M
PET PROBES FOR IMAGING THE VESICULAR ACETYLCHOLINE TRANSPORTERR01NS075527 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2011 to 2021
$4.9M
Parkinson Disease Clinical Subtypes: Validation, Clinical Utility, and Biological CorrelatesR01NS097437 · NINDS · WASHINGTON UNIVERSITY · PI MEGHAN C CAMPBELL · 2017 to 2026
$4.1M
Development and Translation of a PET Tracer for Specific and Early Detection of Alzheimer's DiseaseRF1AG064937 · NIA · WASHINGTON UNIVERSITY · PI BENZINGER, TAMMIE LEE SMITH, SHARMA, VIJAY · 2019 to 2019
$3.8M
Neuroinflammatory Biomarkers for Nigrostriatal InjuryR01NS107281 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES · 2019 to 2023
$3.3M
NOVEL PET MARKERS OF COGNITIVE IMPAIRMENT IN MANGANESENEUROTOXICITYR01ES029524 · NIEHS · WASHINGTON UNIVERSITY · PI CRISWELL, SUSAN · 2019 to 2023
$3.3M
Multi-tissue High-throughput Proteomic and Genomic Study in Parkinson's DiseaseR01NS118146 · NINDS · WASHINGTON UNIVERSITY · PI BENITEZ, BRUNO · 2020 to 2025
$3.2M
Neuroimaging of PDE10AR01NS103957 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES, TU, ZHUDE · 2017 to 2021
$3.1M
NCATS NIH HHS U54 TR001456NCCIH NIH HHS R61 AT010753NIA NIH HHS R01 AG050263NIA NIH HHS R01 AG065214NIA NIH HHS RF1 AG064937NIEHS NIH HHS R01 ES029524NIGMS NIH HHS R01 GM109899NINDS NIH HHS R01 NS075321NINDS NIH HHS R01 NS075527NINDS NIH HHS R01 NS092865NINDS NIH HHS R01 NS097437NINDS NIH HHS R01 NS097799NINDS NIH HHS R01 NS103957NINDS NIH HHS R01 NS107281NINDS NIH HHS R01 NS109487NINDS NIH HHS R01 NS118146NINDS NIH HHS RF1 NS075321NINDS NIH HHS U10 NS077366NINDS NIH HHS U10 NS077384NINDS NIH HHS U19 NS110456NINDS NIH HHS U54 NS065701NINDS NIH HHS U54 NS116025
6 · The paper itself

Abstract

backgroundHead tremor (HT) is a common feature of cervical dystonia (CD), usually quantified by subjective observation. Technological developments offer alternatives for measuring HT severity that are objective and amenable to automation.

objectivesOur objectives were to develop CMOR (Computational Motor Objective Rater; a computer vision-based software system) to quantify oscillatory and directional aspects of HT from video recordings during a clinical examination and to test its convergent validity with clinical rating scales.

methodsFor 93 participants with isolated CD and HT enrolled by the Dystonia Coalition, we analyzed video recordings from an examination segment in which participants were instructed to let their head drift to its most comfortable dystonic position. We evaluated peak power, frequency, and directional dominance, and used Spearman's correlation to measure the agreement between CMOR and clinical ratings.

resultsPower averaged 0.90 (SD 1.80) deg

conclusionsWe demonstrate a new objective method to measure HT severity that requires only conventional video recordings, quantifies the complexities of HT in CD, and exhibits convergent validity with clinical severity ratings.

Indexed as

Dystonic DisordersTorticollisComputersHumansTremorVideo RecordingComputer visionHead tremorSeverity ratingTWSTRSVideo

Identifiers

PMID35101766
PMCPMC9059761
OpenAlexW4206968265

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.