Evidence map›Paper›PMID 35101413›Full record

ArticleTrends in cancer2022

Understanding the role of sex hormones in cancer for the transgender community.

Sarah S Jackson, Kate Z Nambiar, Stewart O'Callaghan, Alison May Berner

Open access · greenAbstract read
In one paragraph

Article in Trends in cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Sweat components as a promising monitoring tool for systemic diseases.The journal of physiological sciences : JPS · 2026
    Review
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  8. Cancer risk among transgender adults: A growing population with unmet needs.Acta obstetricia et gynecologica Scandinavica · 2023
    Article
  9. Prevalence of cancer risk factors among transgender and gender diverse individuals: a cross-sectional analysis using UK primary care data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Sarah S JacksonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Kate Z NambiarBrighton & Sussex University Hospitals NHS Trust, Brighton, UK; Welsh Gender Service, Cardiff and Vale University Health Board, Cardiff, UK.
Stewart O'CallaghanLive Through This Charity, London, UK.
Alison May BernerBarts Cancer Institute, Queen Mary University of London, London, UK; Gender Identity Clinic, Tavistock and Portman NHS Foundation Trust, London, UK. Electronic address: alison.berner@nhs.net.
Cardiff and Vale University Health Board · GBNational Cancer Institute · USThe Tavistock and Portman NHS Foundation Trust · GB

Funding

Descriptive Studies and Record LinkageZIACP010183 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SHIELS, MEREDITH · 2009 to 2025
$10.7M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Sex hormones are crucial for the body's development and function. Therefore, many transgender people seek hormone therapy as part of their transition. However, sex hormones modulate cancer risk. Studying sex hormones in cisgender and transgender populations will improve our knowledge of their biological role in cancer and reduce health disparities.

Indexed as

NeoplasmsTransgender PersonsTranssexualismFemaleGonadal Steroid HormonesHumansMaleGonadal Steroid Hormonescancer riskoestrogensex hormonessex steroidstestosteronetransgender

Identifiers

PMID35101413
PMCPMC8930500
OpenAlexW4210702120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.