Evidence map›Paper›PMID 35101396›Full record

ArticleEnvironmental research2022

Modification of associations between indoor particulate matter and systemic inflammation in individuals with COPD.

Emma Busenkell, Christina M Collins, Marilyn L Moy, Jaime E Hart, Stephanie T Grady, Brent A Coull, Joel D Schwartz, Petros Koutrakis, Eric Garshick

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Emma BusenkellResearch and Development Service, VA Boston Healthcare System, Boston, MA, USA.
Christina M CollinsResearch and Development Service, VA Boston Healthcare System, Boston, MA, USA.
Marilyn L MoyPulmonary, Allergy, Sleep, and Critical Care Medicine Section, Medical Service, VA Boston Healthcare System, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Jaime E HartHarvard Medical School, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Stephanie T GradyBoston University School of Public Health, Boston, MA, USA.
Brent A CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Joel D SchwartzHarvard Medical School, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Eric GarshickPulmonary, Allergy, Sleep, and Critical Care Medicine Section, Medical Service, VA Boston Healthcare System, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: eric.garshick@va.gov.
Brigham and Women's Hospital · USHarvard University · USVA Boston Healthcare System · USBoston University · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
COPD and Response to Traffic Related ParticlesR01ES019853 · NIEHS · HARVARD MEDICAL SCHOOL · PI GARSHICK, ERIC · 2012 to 2016
$3.1M
Retrospective assessment of radon progeny and pollution effects in COPDR21ES029637 · NIEHS · HARVARD MEDICAL SCHOOL · PI GARSHICK, ERIC · 2019 to 2020
$453k
EPA R835872NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES019853NIEHS NIH HHS R21 ES029637
6 · The paper itself

Abstract

rationaleLittle is known about personal characteristics and systemic responses to particulate pollution in patients with COPD.

objectivesAssess whether diabetes, obesity, statins and non-steroidal anti-inflammatory medications (NSAIDs) modify associations between indoor black carbon (BC) and fine particulate matter ≤2.5 μm in diameter (PM

methods144 individuals with COPD without current smoking and without major in-home combustion sources were recruited at Veterans Affairs Boston Healthcare System. PM

resultsMedian (25%ile, 75%ile) indoor BC and PM

conclusionsAssociations between indoor BC and PM

Indexed as

Air PollutantsAir PollutionPulmonary Disease, Chronic ObstructiveC-Reactive ProteinEnvironmental ExposureHumansInflammationParticulate MatterSootAir PollutantsC-Reactive ProteinParticulate MatterSootBlack carbonCOPDCRPDiabetesStatins

Identifiers

PMID35101396
PMCPMC9159533
OpenAlexW4210607939

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.