Evidence map›Paper›PMID 35100797›Full record

ArticleAnaesthesiology intensive therapy2021

Convalescent plasma for COVID-19 in the intensive care unit.

Kazım Rollas, Ömer Emgin, Taner Çalışkan, Işıl K Güldoğan, Çiler Zincircioğlu, Gürsel Ersan, İsa Sahar, Aykut Sarıtaş, Uğur Uzun, Nimet Senoğlu

Open access · diamondAbstract read
In one paragraph

Article in Anaesthesiology intensive therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kazım RollasDepartment of Anaesthesiology Intensive Care, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
Ömer EmginDepartment of Anaesthesiology Intensive Care, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
Taner ÇalışkanDepartment of Anaesthesiology Intensive Care, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
Işıl K GüldoğanDepartment of Anaesthesiology Intensive Care, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
Çiler ZincircioğluDepartment of Anaesthesiology Intensive Care, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
Gürsel ErsanDepartment of Infectious Diseases and Clinical Microbiology, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
İsa SaharDepartment of Anaesthesiology Intensive Care, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
Aykut SarıtaşDepartment of Anaesthesiology Intensive Care, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
Uğur UzunDepartment of Anaesthesiology Intensive Care, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
Nimet SenoğluDepartment of Anaesthesiology Intensive Care, S.B.Ü. Tepecik Training and Research Hospital, İzmir, Turkey.
Izmir Tepecik Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe aimed to investigate the clinical features and mortality of critically ill patients treated with convalescent plasma for COVID-19 in the intensive care unit (ICU). MATERIAL AND

methodsWe retrospectively collected clinical and laboratory data of COVID-19 patients treated in the ICU. The patients were divided into two groups: those who received convalescent plasma and those who did not. We evaluated changes in the laboratory parameters and PaO2/FiO2 of the patients in the convalescent plasma group on days 0, 7, and 14.

resultsA total of 188 patients were included, 89 of whom received convalescent plasma. There were no significant differences in length of hospitalization [median: 17 vs. 16 days, P = 0.13] or 28-day mortality between the two groups (59% vs. 65%, P = 0.38). The ICU stay of patients who received convalescent plasma was longer (P = 0.001). The dynamics of the laboratory parameters of 44 patients in the convalescent plasma group, who were still in intensive care on the 14th day, were analysed. There was no differences in CRP or PaO2/FiO2 on day 0, 7 or 14 (P = 0.12; P = 0.10, respectively).

conclusionsConvalescent plasma treatment was not associated with shorter hospitalisation or lower mortality in patients diagnosed with COVID-19. However, the ICU stay was longer in patients who received convalescent plasma.

Indexed as

COVID-19COVID-19 SerotherapyHumansImmunization, PassiveIntensive Care UnitsLength of StayRetrospective StudiesSARS-CoV-2COVID-19immune plasmaintensive care.mortalitypneumonia

Identifiers

PMID35100797
PMCPMC10172937
OpenAlexW4200429979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.