Evidence map›Paper›PMID 35100437›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2022

Extrasystoles or short bradycardias of the newborn seldom require subsequent 24-hour electrocardiographic monitoring.

Asta Uusitalo, Antti Tikkakoski, Miika Reinikainen, Pieta Lehtinen, Kaisa Ylänen, Päivi Korhonen, Tuija Poutanen

Open access · hybridAbstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Asta UusitaloDepartment of Paediatrics, Tampere University Hospital, Tampere, Finland.ORCID 0000-0001-6620-360X
Antti TikkakoskiDepartment of Clinical Physiology and Nuclear Medicine, Tampere University Hospital, Tampere, Finland.
Miika ReinikainenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Pieta LehtinenDepartment of Clinical Physiology and Nuclear Medicine, Tampere University Hospital, Tampere, Finland.
Kaisa YlänenDepartment of Paediatrics, Tampere University Hospital, Tampere, Finland.
Päivi KorhonenDepartment of Paediatrics, Tampere University Hospital, Tampere, Finland.
Tuija PoutanenDepartment of Paediatrics, Tampere University Hospital, Tampere, Finland.
Tampere University · FITampere University Hospital · FI

Funding

Competitive State ResearchFoundation for Pediatric ResearchInstrumentarium Science Foundation
6 · The paper itself

Abstract

aimTo retrospectively assess the indications for and findings on 24-hour electrocardiographic (Holter) monitoring in newborns, focussing on bradycardias and extrasystoles.

methodsData included 337 term-born infants. Holter indications were categorised into bradycardias below 80 beats per minute, extrasystoles, any tachycardia and other. Heart rate below 60 beats per minute, pathological atrioventricular conduction, supraventricular or ventricular tachycardia, or either atrial premature contractions over 10% or ventricular premature contractions over 5% of total beats were defined as significant arrhythmia on Holter.

resultsThe median age was 6 days (range: 2-62 days). Bradycardia (42%) or extrasystoles (32%) were the most common Holter indications. Fifty-three infants (16%) had significant arrhythmia on Holter. Heart disease or 12-lead electrocardiogram expressing extrasystoles or conduction abnormalities were associated with significant arrhythmias (p = 0.046 and p < 0.001, respectively). Twenty-seven of 109 infants (25%) with extrasystoles as a Holter indication had abnormal Holter results, but only seven (6.4%) had significant arrhythmia on Holter if the 12-lead electrocardiogram was normal. No pathology was found behind bradycardias below 80 beats per minute in the absence of heart disease.

conclusionAmong term newborns with extrasystoles or bradycardias, Holter monitoring could be targeted to infants with heart disease or abnormal electrocardiograms.

Indexed as

BradycardiaHeart DiseasesArrhythmias, CardiacCardiac Complexes, PrematureChildElectrocardiographyHumansInfant, NewbornRetrospective StudiesarrhythmiabradycardiaextrasystolesHolterneonatal

Identifiers

PMID35100437
PMCPMC10138749
OpenAlexW4205754768

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.