Evidence map›Paper›PMID 35100080›Full record

ArticleCell cycle (Georgetown, Tex.)2022

TRPM2-AS promotes the malignancy of osteosarcoma cells by targeting miR-15b-5p/PPM1D axis.

Yingchun Cai, Yudan Yang, Xudong Zhang, Qingqing Ma, Mengyi Li

Open access · greenAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Osteosarcoma in a ceRNET perspective.Journal of biomedical science · 2024
    Review
  4. Journal of Cancer · 2024
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yingchun CaiDepartment of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yudan YangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xudong ZhangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Qingqing MaDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mengyi LiDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS) is a malignant tumor with a low survival rate and a high incidence rate worldwide. Although research has reported the involvement of long non-coding RNAs (lncRNAs) in the pathogenesis of OS cells, the role of TRPM2-AS, miR-15b-5p, and PPM1D in OS progression remains unclear. This study aimed to examine the interaction of the TRPM2-AS/miR-15b-5p/PPM1D axis in OS cells to gain new insights into the molecular mechanism and pathogenesis of OS. After performing

Indexed as

Bone NeoplasmsMicroRNAsOsteosarcomaTRPM Cation ChannelsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansProtein Phosphatase 2CMicroRNAsPPM1D protein, humanProtein Phosphatase 2CTRPM2 protein, humanTRPM Cation ChannelsmiR-15b-5posteosarcomaPPM1DTRPM2-AS

Identifiers

PMID35100080
PMCPMC8973373
OpenAlexW4210469803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.