ArticlePlant physiology2022
Heinz-resistant tomato cultivars exhibit a lignin-based resistance to field dodder (Cuscuta campestris) parasitism.
Article in Plant physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 35 citations in OpenAlex.
- An integrated framework to elucidate mechanisms underlying host-branched broomrape infection.Plant & cell physiology · 2026Article
- Parasitic Plant-Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Cell Wall Dynamics in Haustorial Development ofInternational journal of molecular sciences · 2026Article
- Prehaustoria of root hemiparasites Rhinanthus minor and Odontites vernus (Orobanchaceae) produce lignin-rich interfacial deposits closely resembling those of attached haustoria.Annals of botany · 2026Article
- Broomrapes in Major Mediterranean Crops: From Management Strategies to Novel Approaches for Next-Generation Control.Biotech (Basel (Switzerland)) · 2025Review
- Striga hermonthica induces lignin deposition at the root tip to facilitate prehaustorium formation and obligate parasitism.Plant communications · 2025Article
- Secretory Proteins Are Involved in the Parasitism of Melon byPlants (Basel, Switzerland) · 2024Article
- Use of CRISPR Technology in Gene Editing for Tolerance to Biotic Factors in Plants: A Systematic Review.Current issues in molecular biology · 2024Review
- Extracellular Self- and Non-Self DNA Involved in Damage Recognition in the Mistletoe Parasitism of Mesquite Trees.International journal of molecular sciences · 2023Article
- The genetic basis of plants' battle against witchweeds: linking immune responses to distinct resistance mechanisms.Journal of experimental botany · 2023Article
- The plant vampire diaries: a historic perspective on Cuscuta research.Journal of experimental botany · 2023Review
- Host Resistance to Parasitic Plants-Current Knowledge and Future Perspectives.Plants (Basel, Switzerland) · 2023Review
- Genomic and Epigenomic Mechanisms of the Interaction between Parasitic and Host Plants.International journal of molecular sciences · 2023Review
- Phenotypic and histological analyses on the resistance of melon toFrontiers in plant science · 2023Article
- Transcriptome analysis reveals defense-related genes and pathways during dodder (Frontiers in genetics · 2023Article
- CRISPR gene editing to improve crop resistance to parasitic plants.Frontiers in genome editing · 2023Review
- Article
- Article
- An artificial host system enables the obligate parasite Cuscuta campestris to grow and reproduce in vitro.Plant physiology · 2022Article
- Parasite-resistant ketchup! Lignin-based resistance to parasitic plants in tomato.Plant physiology · 2022Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cuscuta species (dodders) are agriculturally destructive, parasitic angiosperms. These parasitic plants use haustoria as physiological bridges to extract nutrients and water from hosts. Cuscuta campestris has a broad host range and wide geographical distribution. While some wild tomato relatives are resistant, cultivated tomatoes are generally susceptible to C. campestris infestations. However, some specific Heinz tomato (Solanum lycopersicum) hybrid cultivars exhibit resistance to dodders in the field, but their defense mechanism was previously unknown. Here, we discovered that the stem cortex in these resistant lines responds with local lignification upon C. campestris attachment, preventing parasite entry into the host. Lignin Induction Factor 1 (LIF1, an AP2-like transcription factor), SlMYB55, and Cuscuta R-gene for Lignin-based Resistance 1, a CC-NBS-LRR (CuRLR1) are identified as factors that confer host resistance by regulating lignification. SlWRKY16 is upregulated upon C. campestris infestation and potentially negatively regulates LIF1 function. Intriguingly, CuRLR1 may play a role in signaling or function as an intracellular receptor for receiving Cuscuta signals or effectors, thereby regulating lignification-based resistance. In summary, these four regulators control the lignin-based resistance response in specific Heinz tomato cultivars, preventing C. campestris from parasitizing resistant tomatoes. This discovery provides a foundation for investigating multilayer resistance against Cuscuta species and has potential for application in other essential crops attacked by parasitic plants.
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