Evidence map›Paper›PMID 35099368›Full record

ArticleJournal of medical microbiology2022

Prolonged SARS-CoV-2 nucleic acid conversion time in military personnel outbreaks with presence of specific IgG antibodies.

Jhonnatan Reales Gonzalez, Diego Prada Cardozo, Sheryll Corchuelo, Gabriela Zabaleta, Zonia Alarcón, Maria T Herrera Sepulveda, Katherine Laiton Donato, Carlos Franco Muñoz, Diego A Alvarez Diaz, Yesith Guillermo Toloza Perez and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Jhonnatan Reales GonzalezGrupo de Genómica De Microorganismos Emergentes. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Diego Prada CardozoGrupo de Genómica De Microorganismos Emergentes. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Sheryll CorchueloGrupo de Morfología Celular. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Gabriela ZabaletaGrupo de Microbiología. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Zonia AlarcónGrupo de Microbiología. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Maria T Herrera SepulvedaGrupo de Genómica De Microorganismos Emergentes. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Katherine Laiton DonatoGrupo de Genómica De Microorganismos Emergentes. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Carlos Franco MuñozGrupo de Genómica De Microorganismos Emergentes. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Diego A Alvarez DiazGrupo de Genómica De Microorganismos Emergentes. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Yesith Guillermo Toloza PerezGrupo de Salud Ambiental y Laboral. Subdirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Ronald LópezGrupo de Salud Ambiental y Laboral. Subdirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Jeadran Malagón RojasGrupo de Salud Ambiental y Laboral. Subdirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Giovanna BrescianiDirección de Sanidad, Armada Nacional de Colombia, Bogotá, Colombia.
Marcela MercadoGrupo de Genómica De Microorganismos Emergentes. Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá, Colombia.
Instituto Nacional de Salud · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is transmitted person-to-person mainly by close contact or droplets from respiratory tract. However, the actual time of viral shedding is still uncertain as well as the different routes of transmission. We aimed to characterize RNA shedding from nasopharyngeal and rectal samples in prolonged cases of mild COVID-19 in young male soldiers. Seventy patients from three different military locations were monitored after recommending to follow more strict isolation measures to prevent the spread of the virus. Then, nasopharyngeal, rectal, and blood samples were taken. SARS-CoV-2 RNA was detected by RT-PCR and specific antibodies by chemiluminescent immunoassays. The median nucleic acid conversion time (NACT) was 60 days (IQR: 7-85 days). Rectal swabs were taken in 60 % of patients. Seven patients (10 %) were positive in nasopharyngeal and rectal swabs, and five (7.14 %) remained positive in rectal swabs, but negative in nasopharyngeal samples. Four patients (5.71 %) that had been discharged, were positive again after 15 days. No significant difference was found in nucleic acid conversion time between age groups nor clinical classification. Maintaining distancing among different positive patients is essential as a possible re-exposure to the virus could cause a longer nucleic acid conversion time in SARS-COV-2 infections.

Indexed as

COVID-19Antibodies, ViralDisease OutbreaksHumansImmunoglobulin GMaleMilitary PersonnelRNA, ViralSARS-CoV-2Virus SheddingAntibodies, ViralImmunoglobulin GRNA, Viralfalse-recoverednucleic acid conversion timeProlonged COVID-19rectal swabsre-exposureRNA shedding

Identifiers

PMID35099368
PMCPMC8895548
OpenAlexW4210551447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.