Evidence map›Paper›PMID 35099252›Full record

ArticlePhysiological research2021

Short-term arterial compliance changes in the context of systolic blood pressure influence.

D Svec, B Czippelova, J Cernanova Krohova, N Mazgutova, R Wiszt, Z Turianikova, L Matuskova, M Javorka

Abstract readComparative Study
In one paragraph

Article in Physiological research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

D SvecDepartment of Physiology Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic. svec70@uniba.sk.
B Czippelova
J Cernanova Krohova
N Mazgutova
R Wiszt
Z Turianikova
L Matuskova
M Javorka

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial compliance (C) is a complex parameter influencing ventricular-arterial coupling depending on structural (arterial wall remodeling) and functional (blood pressure, smooth muscles tone) changes. Based on Windkessel model, C can be calculated as the ratio of a time constant Tau characterizing diastolic blood pressure decay and total peripheral resistance (TPR). The aim of this study was to assess changes of C in the context of systolic arterial pressure (SAP) perturbations during four physiological states (supine rest, head-up tilt, supine recovery, mental arithmetic). In order to compare pressure independent changes of C a new index of C120 was proposed predicting C value at 120 mm Hg of SAP. Eighty-one healthy young subjects (48 f, average age 18.6 years) were examined. Hemodynamic parameters were measured beat-to-beat using volume-clamp photoplethysmographic method and impedance cardiography. We observed that C was strongly related to SAP values on the beat-to-beat time scale. Interestingly, C120 decreased significantly during stress phases. In conclusion, potential changes of SAP should be considered when measuring C. Arterial compliance changes in the opposite direction to TPR pointing towards influence of vascular tone changes on its value.

Indexed as

Arterial PressureVascular StiffnessAdaptation, PhysiologicalAdolescentFemaleHealthy VolunteersHumansMaleMathematical ConceptsModels, CardiovascularPatient PositioningSupine PositionSystoleTilt-Table TestTime FactorsVascular Resistance

Identifiers

PMID35099252
PMCPMC8884402

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.