Evidence map›Paper›PMID 35098812›Full record

ArticleAnnals of medicine2022

Prevalence and risk factors of retro-styloid lymph node metastasis in oropharyngeal carcinoma.

Ryo Toya, Tetsuo Saito, Yoshiyuki Fukugawa, Tomohiko Matsuyama, Tadashi Matsumoto, Shinya Shiraishi, Daizo Murakami, Yorihisa Orita, Toshinori Hirai, Natsuo Oya

Open access · goldAbstract read
In one paragraph

Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ryo ToyaDepartment of Radiation Oncology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0000-0001-9764-5718
Tetsuo SaitoDepartment of Radiation Oncology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Yoshiyuki FukugawaDepartment of Radiation Oncology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Tomohiko MatsuyamaDepartment of Radiation Oncology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Tadashi MatsumotoDepartment of Radiation Oncology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Shinya ShiraishiDepartment of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Daizo MurakamiDepartment of Otolaryngology-Head and Neck Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Yorihisa OritaDepartment of Otolaryngology-Head and Neck Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Toshinori HiraiDepartment of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Natsuo OyaDepartment of Radiation Oncology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Kumamoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSupporting data defining the selection criteria of level VIIb for inclusion in the target volume in radiotherapy (RT) planning are insufficient. We evaluated the prevalence of level VIIb retro-styloid lymph node metastasis (RSLNM) and associated risk factors in patients with oropharyngeal carcinoma (OPC). MATERIALS AND

methodsWe retrospectively reviewed pre-treatment [

resultsRSLNM was confirmed in 18 (13%) patients. All RSLNMs were located within level VIIb on the planning CT images. No patients exhibited LNM in contralateral level VIIb. Furthermore, no patients with negative or single ipsilateral cervical LNM had RSLNM. Fisher's exact test revealed that smoking status (

conclusionsRSLNM is relatively common in patients with OPC with a prevalence rate of approximately 10%. The prevalence of RSLNM in patients with negative or single ipsilateral cervical LNM and contralateral RSLNM is extremely low; therefore, level VIIb can be excluded from the target volume in such patients. LN ≥15 mm in the upper limit of ipsilateral level II is a risk factor for RSLNM. Ipsilateral level VIIb should be included in the target volume for patients with this risk factor.KEY MESSAGERetro-styloid lymph node metastasis (RSLNM) prevalence is ∼10% in oropharyngeal carcinoma.Lymph node ≥15 mm in ipsilateral level II upper limit is a risk factor for RSLNM.

Indexed as

CarcinomaHumansLymphatic MetastasisPrevalenceRetrospective StudiesRisk Factorsclinical target volumeHead and neck cancerlymph node metastasisoropharyngeal carcinomapositron emission tomographyradiotherapyretro-styloid lymph node

Identifiers

PMID35098812
PMCPMC8812754
OpenAlexW4210400664

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.