Evidence map›Paper›PMID 35098730›Full record

ArticleCirculation. Cardiovascular quality and outcomes2022

Relationship Between Social Determinants of Health and Antihypertensive Medication Adherence in a Medicaid Cohort.

Marcee E Wilder, Zhanonian Zheng, Scott L Zeger, Angelo Elmi, Richard J Katz, Yixuan Li, Melissa L Mccarthy

Open access · bronzeAbstract read
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

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  10. Prognosis of apparent treatment-resistant hypertension and poor adherence: a nationwide cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Observational
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  18. Financial hardship and major adverse cardiovascular events: The role of advanced cardiac imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Marcee E WilderDepartment of Emergency Medicine (M.E.W., M.L.M.), The George Washington University, Medical Faculty Associates, Washington, DC.ORCID 0000-0001-6508-4573
Zhanonian ZhengDepartment of Health Policy and Management (Z.Z., Y.L., M.L.M.), The George Washington University, Washington, DC.
Scott L ZegerDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (S.L.Z.).ORCID 0000-0001-8907-1603
Angelo ElmiDepartment of Epidemiology and Biostatistics (A.E.), Milken Institute School of Public Health, The George Washington University, Washington, DC.
Richard J KatzDivision of Cardiology (R.J.K.), The George Washington University, Medical Faculty Associates, Washington, DC.ORCID 0000-0002-4127-2331
Yixuan LiDepartment of Health Policy and Management (Z.Z., Y.L., M.L.M.), The George Washington University, Washington, DC.ORCID 0000-0002-3550-8192
Melissa L MccarthyDepartment of Emergency Medicine (M.E.W., M.L.M.), The George Washington University, Medical Faculty Associates, Washington, DC.ORCID 0000-0002-0092-2748
George Washington University · USWashington University Medical Center · USJohns Hopkins University · USMilken Institute · US

Funding

Integrating Social Determinants of Health Into Risk Adjustment Models: An Opportunity to Improve Care Coordination Strategies For Medicaid BeneficiariesR01MD011607 · NIMHD · GEORGE WASHINGTON UNIVERSITY · PI MCCARTHY, MELISSA L · 2017 to 2020
$2.5M
NIMHD NIH HHS R01 MD011607
6 · The paper itself

Abstract

backgroundLittle is known about the relationship between social determinants of health (SDH) and medication adherence among Medicaid beneficiaries with hypertension.

methodsWe conducted a posthoc subgroup analysis of 3044 adult Medicaid beneficiaries who enrolled in a parent prospective cohort study and had a diagnosis of hypertension based on their Medicaid claims during a 24-month period before study enrollment. We calculated the proportion of days covered by at least one antihypertensive medication during the first 12 months after study enrollment using the prescription claims data. We measured numerous SDH at the time of study enrollment and we categorized our hypertension cohort into 4 social risk groups based on their response profiles to the SDH variables. We compared the mean proportion of days covered by the different levels of the SDH factors. We modeled the odds of being covered by an antihypertensive medication daily throughout the follow-up period by social risk group, adjusted for age, sex, and disease severity using a generalized linear model.

resultsThe nonrandom sample was predominately Black (93%), female (62%) and had completed high school (77%). The mean proportion of days covered varied significantly by different SDH, such as food insecurity (49%-56%), length of time living at present place (47%-57%), smoking status (50%-56%), etc. Social risk group was a significant predictor of medication adherence. Participants in the 2 groups with the most social risks were 36% (adjusted odds ratio=0.64 [95% CI, 0.53-0.78]) and 20% (adjusted odds ratio=0.80 [95% CI, 0.70-0.93]) less adherent to their hypertension therapy compared with participants in the group with the fewest social risks.

conclusionsSocial risks are associated with lower antihypertensive medication adherence in the Medicaid population.

Indexed as

Antihypertensive AgentsHypertensionAdultCohort StudiesFemaleHumansMedicaidMedication AdherenceProspective StudiesRetrospective StudiesSocial Determinants of HealthUnited StatesAntihypertensive Agentshypertensionmedication adherencepopulationsocial determinants of health

Identifiers

PMID35098730
PMCPMC8847233
OpenAlexW4210565824

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.